Triple-drug inhaler aims to tame severe asthma in teens and adults

NCT ID NCT04609904

Completed Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Jul 02, 2026 · Last updated Jul 02, 2026

Summary

This study tests whether a three-in-one inhaler (budesonide, glycopyrronium, and formoterol) works better than two-drug inhalers for people aged 12 to 80 with asthma that is not well controlled by their current treatment. Participants receive either the triple inhaler, a two-drug version, or an existing two-drug inhaler (Symbicort) for up to 24 weeks. The main goals are to measure improvements in lung function and reductions in severe asthma attacks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Budesonide, glycopyrronium, and formoterol fumarate metered dose inhaler

What this could lead to

If successful, this triple-combination inhaler could offer better asthma control and fewer severe attacks for people whose asthma is not well managed with standard two-drug inhalers.

What could go wrong

This is a large Phase 3 trial, but results may not apply to all asthma patients. The added benefit over existing treatments may be modest, and side effects from the extra drug are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

asthma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ASTHMA

More trials for these conditions

Other studies related to the condition(s) this trial covers.

Contacts and locations

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Chandler, Arizona, 85224, United States
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Tempe, Arizona, 85283, United States
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Tucson, Arizona, 85741, United States
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Hot Springs, Arkansas, 71913, United States
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Bakersfield, California, 93301, United States
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