New triple inhaler could offer better asthma control for millions

NCT ID NCT06372496

Ongoing Disease control Sponsor: GlaxoSmithKline Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a triple-combination inhaler (FF/UMEC/VI) works better than standard dual therapy (ICS/LABA) for adults whose asthma is not well controlled. About 1,366 participants will use either the triple inhaler or their usual treatment for 24 weeks. The main goal is to see if lung function improves more with the triple inhaler.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Fluticasone furoate/umeclidinium bromide/vilanterol trifenatate (a triple-combination inhaler)

What this could lead to

If successful, this could show that the triple-combination inhaler controls asthma better than standard dual therapy, potentially reducing symptoms and improving lung function.

What could go wrong

This is a Phase 4 study comparing existing drugs, so no breakthrough is expected. Results may show only modest benefits, and individual responses can vary.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

asthma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ASTHMA

Contacts and locations

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Locations

GSK Investigational Site

Centreville, Alabama, 35042, United States
GSK Investigational Site

Little Rock, Arkansas, 72205, United States
GSK Investigational Site

Newport Beach, California, 92663, United States
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Newark, Delaware, 08901, United States
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Clearwater, Florida, 33765-2150, United States
GSK Investigational Site

Florida City, Florida, 32819, United States
GSK Investigational Site

Miami, Florida, 15801, United States
GSK Investigational Site

Miami, Florida, 33126, United States
GSK Investigational Site

Miami, Florida, 33135, United States
GSK Investigational Site

Miami, Florida, 33173, United States
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North Miami Beach, Florida, 33169, United States
GSK Investigational Site

Palm Springs, Florida, 33406, United States
GSK Investigational Site

Port Charlotte, Florida, 33952, United States
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Tallahassee, Florida, 32308, United States
GSK Investigational Site

Normal, Illinois, 61761, United States
GSK Investigational Site

New Orleans, Louisiana, 20852, United States
GSK Investigational Site

Bangor, Maine, 04401, United States
GSK Investigational Site

Detroit, Michigan, 48202, United States
GSK Investigational Site

Warren, Michigan, 48088, United States
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Missoula, Montana, 59804, United States
GSK Investigational Site

Papillion, Nebraska, 68046, United States
GSK Investigational Site

Brick, New Jersey, 08724, United States
GSK Investigational Site

Linwood, New Jersey, 08221, United States
GSK Investigational Site

New Windsor, New York, 12553, United States
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Asheville, North Carolina, 28801, United States
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Charlotte, North Carolina, 28273, United States
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Greenville, North Carolina, 27834, United States
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Winston-Salem, North Carolina, 27104, United States
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Cincinnati, Ohio, 45231, United States
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Philadelphia, Pennsylvania, 19140, United States
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Pittsburgh, Pennsylvania, 15241, United States
GSK Investigational Site

Rock Hill, South Carolina, 29732, United States
GSK Investigational Site

Spartanburg, South Carolina, 29303, United States
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Beaumont, Texas, 77701, United States
GSK Investigational Site

Dallas, Texas, 75225, United States
GSK Investigational Site

Bellingham, Washington, 98225, United States
GSK Investigational Site

Buenos Aires, C1128AAF, Argentina
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Buenos Aires, C1192AAW, Argentina
GSK Investigational Site

Buenos Aires, C1425BEN, Argentina
GSK Investigational Site

Buenos Aires, FVH1425, Argentina
GSK Investigational Site

Ciudad Autonoma de Buenos Aire, 1012, Argentina
GSK Investigational Site

Concepción del Uruguay, 3260, Argentina
GSK Investigational Site

Córdoba, X5003DCE, Argentina
GSK Investigational Site

Formosa, 3600, Argentina
GSK Investigational Site

Lujan de Cuyo, 5509, Argentina
GSK Investigational Site

Luján, 6700, Argentina
GSK Investigational Site

Mar del Plata, 7600, Argentina
GSK Investigational Site

Mendoza, 5500, Argentina
GSK Investigational Site

Mendoza, 5577, Argentina
GSK Investigational Site

Mendoza, M5500, Argentina
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Quilmes, 1878, Argentina
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Rosario, 2000, Argentina
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Rosario, S2000 DEJ, Argentina
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Rosario, S2000DBS, Argentina
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San Juan Bautista, 1888, Argentina
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San Miguel de Tucumán, T4000AXL, Argentina
GSK Investigational Site

Santa Fe, 3000, Argentina
GSK Investigational Site

Bruce, Australian Capital Territory, 2617, Australia
GSK Investigational Site

Blacktown, New South Wales, 2148, Australia
GSK Investigational Site

Coffs Harbour, New South Wales, 2450, Australia
GSK Investigational Site

Kanwal, New South Wales, 2259, Australia
GSK Investigational Site

Sydney, New South Wales, 2035, Australia
GSK Investigational Site

Brisbane, Queensland, 4006, Australia
GSK Investigational Site

Osborne Park, Western Australia, 6017, Australia
GSK Investigational Site

Spearwood, Western Australia, 6163, Australia
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Windsor, Ontario, N8X 1T3, Canada
GSK Investigational Site

Trois-Rivières, Quebec, G9A 4P3, Canada
GSK Investigational Site

Chancheng District, Foshan City, 528031, China
GSK Investigational Site

Liwan District, Guangzhou, 510160, China
GSK Investigational Site

North Street, Jiangmen City, 52900, China
GSK Investigational Site

Nanshan District, 518067, China
GSK Investigational Site

Zhuhai, 519099, China
GSK Investigational Site

Fukuoka, 802-0083, Japan
GSK Investigational Site

Fukuoka, 807-8555, Japan
GSK Investigational Site

Fukuoka, 816-0813, Japan
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Fukuoka, 820-8505, Japan
GSK Investigational Site

Fukuoka, 832-0059, Japan
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Gifu, 509-6134, Japan
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Hiroshima, 730-0013, Japan
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Hiroshima, 730-0853, Japan
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Hiroshima, 733-0002, Japan
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Hyōgo, 651-0053, Japan
GSK Investigational Site

Kagawa, 761-8073, Japan
GSK Investigational Site

Kagoshima, 890-0053, Japan
GSK Investigational Site

Kanagawa, 252-0143, Japan
GSK Investigational Site

Kumamoto, 860-8556, Japan
GSK Investigational Site

Kumamoto, 862-0965, Japan
GSK Investigational Site

Matsuyama, 790-0925, Japan
GSK Investigational Site

Miyagi, 980-0871, Japan
GSK Investigational Site

Miyazaki, 880-2112, Japan
GSK Investigational Site

Miyazaki, 889-4304, Japan
GSK Investigational Site

Nagaoka-Shi, 940-0087, Japan
GSK Investigational Site

Niigata, 950-0088, Japan
GSK Investigational Site

Okawa-shi, 831-0016, Japan
GSK Investigational Site

Ōita, Japan
GSK Investigational Site

Shinjuku-kuTokyo, 160-0021, Japan
GSK Investigational Site

Tokyo, 105-0001, Japan
GSK Investigational Site

Tokyo, 142-8666, Japan
GSK Investigational Site

Tokyo, 145-0063, Japan
GSK Investigational Site

Tokyo, 157-0066, Japan
GSK Investigational Site

Tokyo, 160-0017, Japan
GSK Investigational Site

Tokyo, 173-8606, Japan
GSK Investigational Site

Yokohama, 223-0053, Japan
GSK Investigational Site

Busan, 602 702, South Korea
GSK Investigational Site

Daegu, 41404, South Korea
GSK Investigational Site

Seongnam-si Gyeonggi-do, 13620, South Korea
GSK Investigational Site

Seoul, 02841, South Korea
GSK Investigational Site

Seoul, 03080, South Korea
GSK Investigational Site

Seoul, 07061, South Korea
GSK Investigational Site

Seoul, 133-792, South Korea
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Seoul, 158-710, South Korea
GSK Investigational Site

Seoul, 5030, South Korea
GSK Investigational Site

Suwon Kyunggi-do, 16499, South Korea
GSK Investigational Site

Kaohsiung City, 807, Taiwan
GSK Investigational Site

Taichung, 40447, Taiwan
GSK Investigational Site

Taichung, 407219, Taiwan
GSK Investigational Site

Taipei, 10002, Taiwan