Can aspirin or diabetes drugs tame fatty liver? new study reveals results
NCT ID NCT07338331
First seen Jun 27, 2026 · Last updated Aug 14, 2026 · Updated 2 times
Summary
This study looked at whether aspirin or a diabetes drug called an SGLT2 inhibitor (like dapagliflozin) can improve liver health in people with type 2 diabetes and non-alcoholic fatty liver disease. Researchers measured liver enzymes, cholesterol, and liver stiffness (using FibroScan) in 80 adults over 6 months. The goal was to see which treatment better controls liver damage and metabolic symptoms.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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80 people
The number who actually took part.
- Started
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Apr 2023
- Finished
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Sep 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: if one or more the following are present: * Diabetes mellitus, unless receiving only Dapagliflozin for treatment. * Adult individuals (18-65 years) with a clinical diagnosis of NAFLD based on liver ultrasound * No history of alcohol consumption or consumption within 3 months. * Absence of other liver diseases. * No significant renal or gastrointestinal issues that could interfere with treatment. Exclusion Criteria:Patients were excluded from our study if one or more the -following are present: * Pregnancy or breastfeeding. * Active chronic viral hepatitis or autoimmune liver disease. * History of gastrointestinal bleeding or other contraindications for Aspirin. * Severe renal insufficiency. * Alcohol intake
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Faculty of Pharmacy
Banī Suwayf, Beni Suweif Governorate, 0000, Egypt
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