Aspirin after preeclampsia: could a simple pill protect Women's hearts?
NCT ID NCT06168461
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
Women who had preeclampsia are four times more likely to develop heart disease later in life, possibly due to lasting blood vessel damage. This early-phase trial tests whether taking low-dose aspirin (162 mg daily) can improve blood vessel function in 40 women who had preeclampsia within the past five years. Researchers will measure how well blood vessels respond to certain signals, comparing aspirin to a placebo.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Aspirin
- What this could lead to
- If it works, this could point toward a simple, low-cost treatment to lower heart disease risk in women who had preeclampsia.
- What could go wrong
- This is a very early, small trial (40 people) testing short-term effects on blood vessel function, not long-term heart health. Aspirin may not provide lasting benefit.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Iowa
RECRUITINGIowa City, Iowa, 52242, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Depression drug may mend blood vessels damaged by preeclampsia
- Postpartum blood pressure control may stop preeclampsia from leading to lifelong hypertension
- Genetic clues to severe preeclampsia could transform early detection