Could a malaria drug reverse cervical Pre-Cancer?
NCT ID NCT04098744
First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 27 times
Summary
This study tests whether a vaginal insert containing artesunate, a drug originally used for malaria, can help reverse high-grade cervical pre-cancer (CIN2/3) caused by HPV. About 78 women will receive either the drug or a placebo over three 5-day cycles. The main goal is to see if the treatment can shrink the abnormal cells back to normal or low-grade changes by week 17.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Cleveland Clinic Fairview Hospital
RECRUITINGCleveland, Ohio, 44111, United States
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Cleveland Clinic Foundation
RECRUITINGCleveland, Ohio, 44195, United States
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Florida Gynecologic Oncology
RECRUITINGFort Myers, Florida, 33905, United States
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Hillcrest Hospital
RECRUITINGMayfield Heights, Ohio, 44124, United States
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The Harris Health System (L.B.J Hospital)
RECRUITINGHouston, Texas, 77026, United States
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University of Michigan
RECRUITINGAnn Arbor, Michigan, 48109, United States
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University of Texas, M.D. Anderson
RECRUITINGHouston, Texas, 77030, United States
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Conditions
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