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New surgical order may boost pancreatic cancer outcomes

NCT ID NCT07547033

Not yet recruiting Disease control Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether changing the order of steps during a Whipple surgery for pancreatic head cancer can help surgeons remove the tumor more completely and lower the chance of cancer coming back. About 150 adults with operable pancreatic cancer will be randomly assigned to either the standard surgery or the newer 'artery-first' technique. The main goal is to see if the artery-first approach leads to clearer surgical margins, which may improve long-term outcomes.

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Conditions

The condition(s) this trial relates to.

exocrine pancreatic carcinoma pancreatic adenocarcinoma pancreatic ductal adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PANCREATIC ADENOCARCINOMA PANCREATIC HEAD CANCER

Contacts and locations

Locations

  • CHU Amiens

    Amiens, France

  • CHU Angers

    Angers, France

  • CHU Besançon

    Besançon, France

  • CHU Dupuytren 1

    Limoges, France

  • CHU Lille - Hôpital Claude Huriez

    Lille, France

  • CHU Strasbourg

    Strasbourg, France

  • Centre Léon Bérard

    Lyon, France

  • Chu Nantes

    Nantes, France

  • Hôpital Ambroise Paré

    Paris, France

  • Hôpital Beaujon

    Paris, France

  • Hôpital Charles-Nicolle

    Rouen, France

  • Hôpital Claude Huriez

    Lille, France

  • Hôpital Cochin

    Paris, France

  • Hôpital Estaing

    Clermont-Ferrand, France

  • Hôpital François Mitterrand

    Dijon, France

  • Hôpital Haut Lévêque

    Bordeaux, France

  • Hôpital Paul Brousse

    Villejuif, France

  • Hôpital Rangueil

    Toulouse, France

  • Hôpital Saint Eloi

    Montpellier, France

  • Hôpital de la Croix-Rousse

    Lyon, France

  • Hôpital de la Pitié Salpêtrière

    Paris, France

  • Hôpitaux de Brabois

    Nancy, France

  • Institut Gustave Roussy

    Villejuif, France

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