Heart stiffness drug shows promise in Insulin-Resistant adults
NCT ID NCT03837626
First seen Sep 30, 2025 · Last updated May 16, 2026 · Updated 23 times
Summary
This study tested whether amiloride, a drug that blocks a sodium channel (ENaC), can improve artery function and reduce stiffness in overweight adults with insulin resistance. The trial included 137 pre- and postmenopausal women and age-matched men. Researchers measured arterial stiffness using a gold-standard method called carotid-femoral pulse wave velocity.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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University of Missouri Hospital and Clinics
Columbia, Missouri, 65201, United States
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