Robot-Assisted lung biopsy gets a Real-Time check: could boost accuracy and genetic testing

NCT ID NCT07685977

First seen Jul 06, 2026 · Last updated Jul 07, 2026 · Updated 1 time

Summary

This trial tests whether adding rapid onsite evaluation (ROSE) during robotic-assisted bronchoscopy improves the diagnosis of peripheral lung lesions. ROSE lets doctors check biopsy samples immediately under a microscope to confirm they contain enough tissue. The study also looks at whether samples are adequate for next-generation sequencing, which guides personalized treatment. About 400 adults undergoing robotic bronchoscopy for a lung lesion will be randomly assigned to receive ROSE or not.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this approach could make lung biopsies more accurate and reduce the need for repeat procedures, while ensuring enough tissue is collected for genetic testing.
What could go wrong
The trial is still recruiting and results are not yet available. The benefit of rapid onsite evaluation may vary by lesion type or operator experience, and it may not improve outcomes for all patients.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

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Locations

  • Johns Hopkins University

    Baltimore, Maryland, 21287, United States

    Contact

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  • Lahey Hospital and Medical Center

    Burlington, Massachusetts, 01805, United States

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  • Medical University of South Carolina

    Charleston, South Carolina, 29425, United States

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  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

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  • Northwestern Memorial Hospital

    Chicago, Illinois, 60611, United States

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  • Rush University Medical Center

    Chicago, Illinois, 60612, United States

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  • University of North Carolina Medical Center

    Chapel Hill, North Carolina, 27154, United States

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  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37232, United States

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