Can a drug calm severe autism behaviors? new study tests aripiprazole

NCT ID NCT00337571

First seen May 19, 2026 · Last updated May 22, 2026 · Updated 1 time

Summary

This study tested whether aripiprazole, a medication, can reduce serious behavioral problems like irritability and agitation in children and adolescents (ages 6-17) with autistic disorder. 218 participants received either a fixed dose of aripiprazole or a placebo for 8 weeks. The main goal was to see if the drug improved behavior scores compared to placebo.

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Contacts and locations

Locations

  • Bayou City Research, Ltd.

    Houston, Texas, 77007, United States

  • Cambridge Health Alliance

    Medford, Massachusetts, 02139, United States

  • Children'S Hospital Of Michigan

    Detroit, Michigan, 48201, United States

  • Children'S Hospital Of Wisconsin

    Milwaukee, Wisconsin, 53201, United States

  • Children'S Mercy Hospital

    Kansas City, Missouri, 64108, United States

  • Children'S National Medical Center

    Fairfax, Virginia, 22031, United States

  • Clinical Innovations, Inc.

    Huntington Beach, California, 92647, United States

  • Cutting Edge Research

    Oklahoma City, Oklahoma, 73116, United States

  • Dallas Pediatric Neurology Associates

    Dallas, Texas, 75230, United States

  • Duke Child And Family Study Center

    Durham, North Carolina, 27710, United States

  • Harmonex Neuroscience

    Dothan, Alabama, 36303, United States

  • Institute For Behavioral Medicine

    Smyrna, Georgia, 30080, United States

  • Ladders Clinic

    Wellesley, Massachusetts, 02481, United States

  • Marsella, Gregory

    Boca Raton, Florida, 33432, United States

  • Mission Hospitals

    Asheville, North Carolina, 28801, United States

  • Munroe-Meyer Institute

    Omaha, Nebraska, 68198, United States

  • North Shore - Long Island Jewish Health System

    Bethpage, New York, 11714, United States

  • Pacific Institute Of Medical Sciences

    Bothell, Washington, 98011, United States

  • Regions Hospital

    Saint Paul, Minnesota, 55101, United States

  • Richmond Behavioral Associates

    Staten Island, New York, 10312, United States

  • Seaver And New York Autism Center Of Excellence

    New York, New York, 10029, United States

  • Southwest Autism Research And Resource Center

    Phoenix, Arizona, 85006, United States

  • Stanford University School Of Medicine

    Stanford, California, 94305, United States

  • The Children'S Hospital

    Aurora, Colorado, 80045, United States

  • The Nisonger Center

    Columbus, Ohio, 43210, United States

  • University Of Alabama At Birmingham

    Birmingham, Alabama, 35294, United States

  • University Of California-Davis Medical Center

    Sacramento, California, 95817, United States

  • University Of Florida

    Gainesville, Florida, 32611, United States

  • University Of Illinois At Chicago

    Chicago, Illinois, 60606, United States

  • University Of South Florida

    Tampa, Florida, 33613, United States

  • Western Psychiatric Institute And Clinic

    Pittsburgh, Pennsylvania, 15203, United States

Conditions

Explore the condition pages connected to this study.