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Glowing dye could cut bowel leak risk in ovarian cancer surgery

NCT ID NCT04878094

Recruiting now Disease control Sponsor: Memorial Sloan Kettering Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests whether using a fluorescent dye and special camera during ovarian cancer surgery can help surgeons see blood flow in the bowel and reduce the risk of leaks after reconnecting it. About 310 women with ovarian cancer who need bowel surgery will be randomly assigned to get either the dye-guided imaging or standard checks. The goal is to see if this technique lowers the chance of serious complications within 30 days after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Indocyanine Green (ICG) dye
What this could lead to
If it works, this could reduce serious bowel leaks after ovarian cancer surgery, leading to fewer complications and better recovery.
What could go wrong
This is a phase III trial, but the dye and imaging system are already used in other surgeries. The main risk is that it may not significantly lower leak rates compared to standard methods.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

fallopian tube cancer ovarian cancer ovarian carcinoma primary peritoneal carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OVARIAN CANCER OVARIAN CARCINOMA

Contacts and locations

Locations

  • Houston Methodist Cancer Center (Data Collection Only)

    RECRUITING

    Houston, Texas, 77030, United States

  • Jefferson Abington Hospital

    RECRUITING

    Willow Grove, Pennsylvania, 19090, United States

  • Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)

    RECRUITING

    Basking Ridge, New Jersey, 07920, United States

  • Memorial Sloan Kettering Bergen (Limited Protocol Activities)

    RECRUITING

    Montvale, New Jersey, 07645, United States

  • Memorial Sloan Kettering Cancer Center (All Protocol Activities)

    RECRUITING

    New York, New York, 10065, United States

  • Memorial Sloan Kettering Cancer Center @ Suffolk - Commack (Limited Protocol Activities)

    RECRUITING

    Commack, New York, 11725, United States

  • Memorial Sloan Kettering Monmouth (Limited Protocol Activities)

    RECRUITING

    Middletown, New Jersey, 07748, United States

  • Memorial Sloan Kettering Nassau (Limited Protocol Activities)

    RECRUITING

    Uniondale, New York, 11553, United States

  • Memorial Sloan Kettering Westchester (Limited Protocol Activities)

    RECRUITING

    Harrison, New York, 10604, United States

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