Promising liver treatment trial for rare disease pulled before start

NCT ID NCT02900183

First seen Dec 26, 2025 · Last updated May 11, 2026 · Updated 18 times

Summary

This study aimed to test a new drug called ARC-AAT in people with Alpha-1 Antitrypsin Deficiency, a genetic condition that can cause liver and lung damage. The drug was designed to lower harmful protein levels in the blood and liver. However, the trial was withdrawn before any participants were enrolled, so no results are available.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Research Site 1

    Toronto, Ontario, M5T3A9, Canada

  • Research Site 2

    Dublin, Ireland

  • Research Site 3

    Pavia, 27100, Italy

  • Research Site 4

    Malmö, SE-205 02, Sweden

Conditions

Explore the condition pages connected to this study.