New hope for MS muscle stiffness: phase 3 drug trial launches

NCT ID NCT05179577

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests an extended-release tablet called arbaclofen to see if it safely reduces muscle stiffness (spasticity) in people with multiple sclerosis. About 442 adults aged 18 to 65 with MS-related spasticity will receive either the drug or a placebo. The goal is to measure changes in muscle tightness and overall function.

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Conditions

The condition(s) this trial relates to.

multiple sclerosis Muscle Spasticity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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