Could an apple extract fight inflammation and slow aging?

NCT ID NCT07678346

Not yet recruiting Disease control Sponsor: Nutraland USA, Inc. Source: ClinicalTrials.gov ↗

First seen Jul 01, 2026 · Last updated Jul 02, 2026 · Updated 1 time

Summary

This study tests whether a daily apple extract called AppleX™, rich in the compound fisetin, can lower inflammation and improve vitality in adults aged 45 to 70 who have signs of low-grade inflammation. Participants take either the extract or a placebo for 24 weeks. Researchers measure changes in blood inflammation markers, energy levels, joint comfort, and biological aging.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: AppleX™ apple extract (standardized to 15% fisetin)
What this could lead to: If it works, this could point toward a natural supplement to reduce inflammation and support healthier aging.
What could go wrong: This is a small pilot study, so results may not apply widely. The extract may not lower inflammation or affect aging as hoped.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEALTHY ADULT PARTICIPANTS HEALTHY AGING SYSTEMIC INFLAMMATION (HSCRP) VITALITY

Contacts and locations

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Study contacts

Contact

Email: •••••@•••••

Locations

Alethios, Inc.

San Francisco, California, 94109, United States

Contact Email: •••••@•••••

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