Could an apple extract fight inflammation and slow aging?

NCT ID NCT07678346

First seen Jul 01, 2026 · Last updated Jul 01, 2026

Summary

This study tests whether a daily apple extract called AppleX™, rich in the compound fisetin, can lower inflammation and improve vitality in adults aged 45 to 70 who have signs of low-grade inflammation. Participants take either the extract or a placebo for 24 weeks. Researchers measure changes in blood inflammation markers, energy levels, joint comfort, and biological aging.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

AppleX™ apple extract (standardized to 15% fisetin)

What this could lead to

If it works, this could point toward a natural supplement to reduce inflammation and support healthier aging.

What could go wrong

This is a small pilot study, so results may not apply widely. The extract may not lower inflammation or affect aging as hoped.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Alethios, Inc.

    San Francisco, California, 94109, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••