New drug APL-9796 tested for lung blood pressure disorder

NCT ID NCT06846554

Recruiting now Disease control Sponsor: Apollo Therapeutics Ltd Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase 2 trial tests an experimental drug called APL-9796 in 48 adults with pulmonary hypertension (high blood pressure in the lungs). The study aims to see if the drug is safe, tolerable, and effective. Participants receive injections under the skin, and researchers monitor side effects, heart function, and walking ability.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: APL-9796 (an experimental drug given as injections under the skin)
What this could lead to: If successful, this could point toward a new treatment option for pulmonary hypertension, potentially improving heart and lung function.
What could go wrong: This is an early Phase 2 trial with only 48 participants, so results may not apply to everyone. The drug may cause side effects or prove no better than existing treatments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

pulmonary arterial hypertension pulmonary hypertension pulmonary hypertension owing to lung disease and/or hypoxia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PULMONARY ARTERIAL HYPERTENSION

Contacts and locations

Locations

Golden Jubilee Hospital
RECRUITING

Clydebank, United Kingdom
Hammersmith/Imperial Hospital
RECRUITING

London, London, W12 0HS, United Kingdom
Royal Brompton Hospital
RECRUITING

London, United Kingdom
Royal Papworth Hospital
RECRUITING

Cambridge, United Kingdom
Royal United Hospital Bath
RECRUITING

Bath, United Kingdom
Sheffield Teaching Hospitals
RECRUITING

Sheffield, United Kingdom

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