New drug APL-9796 tested for lung blood pressure disorder

NCT ID NCT06846554

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase 2 trial tests an experimental drug called APL-9796 in 48 adults with pulmonary hypertension (high blood pressure in the lungs). The study aims to see if the drug is safe, tolerable, and effective. Participants receive injections under the skin, and researchers monitor side effects, heart function, and walking ability.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

APL-9796 (an experimental drug given as injections under the skin)

What this could lead to

If successful, this could point toward a new treatment option for pulmonary hypertension, potentially improving heart and lung function.

What could go wrong

This is an early Phase 2 trial with only 48 participants, so results may not apply to everyone. The drug may cause side effects or prove no better than existing treatments.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

pulmonary arterial hypertension pulmonary hypertension pulmonary hypertension owing to lung disease and/or hypoxia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Golden Jubilee Hospital

    RECRUITING

    Clydebank, United Kingdom

  • Hammersmith/Imperial Hospital

    RECRUITING

    London, London, W12 0HS, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Royal Brompton Hospital

    RECRUITING

    London, United Kingdom

  • Royal Papworth Hospital

    RECRUITING

    Cambridge, United Kingdom

  • Royal United Hospital Bath

    RECRUITING

    Bath, United Kingdom

  • Sheffield Teaching Hospitals

    RECRUITING

    Sheffield, United Kingdom