Brain scans reveal Anxiety's hidden role in alcohol recovery

NCT ID NCT06793488

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how anxiety affects the brain in people with alcohol use disorder during early and long-term abstinence. Researchers will use fMRI scans and the medication disulfiram (Antabuse) to help participants stay sober. They aim to understand the brain circuits linked to anxiety, which could lead to better support for recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Disulfiram (Antabuse)

What this could lead to

If successful, this could reveal how the brain drives anxiety during alcohol withdrawal, pointing toward better treatments for alcohol use disorder.

What could go wrong

This is a very early, small study (60 people) focused on understanding brain activity, not testing a new treatment. Results may not lead to direct therapies.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

alcohol abuse anxiety disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Columbia University Irving Medical Center

    RECRUITING

    New York, New York, 10019, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••