Brain scans reveal Anxiety's hidden role in alcohol recovery

NCT ID NCT06793488

Recruiting now Knowledge-focused Sponsor: Columbia University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how anxiety affects the brain in people with alcohol use disorder during early and long-term abstinence. Researchers will use fMRI scans and the medication disulfiram (Antabuse) to help participants stay sober. They aim to understand the brain circuits linked to anxiety, which could lead to better support for recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Disulfiram (Antabuse)
What this could lead to: If successful, this could reveal how the brain drives anxiety during alcohol withdrawal, pointing toward better treatments for alcohol use disorder.
What could go wrong: This is a very early, small study (60 people) focused on understanding brain activity, not testing a new treatment. Results may not lead to direct therapies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ALCOHOL USE DISORDER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

alcohol abuse anxiety disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALCOHOL USE DISORDER

Contacts and locations

Locations

Columbia University Irving Medical Center
RECRUITING

New York, New York, 10019, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.