Schizophrenia drug showdown: which pill spares your Cells' power plants?
NCT ID NCT06236451
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed study compared two schizophrenia medications, aripiprazole and risperidone, in 60 patients to see how they affect mitochondria—the energy factories inside cells. Researchers measured changes in mitochondrial activity and related blood markers over 12 weeks. The goal was to understand if these drugs cause cell energy problems that might lead to side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Aripiprazole and Risperidone
What this could lead to
If successful, this could help explain why some antipsychotics cause side effects like movement problems, potentially guiding safer treatment choices.
What could go wrong
This is a small, completed study measuring biological markers, not clinical outcomes. Results may not change treatment or apply to all patients.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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All India Institute of Medical Sciences (AIIMS)
Bhubaneswar, Odisha, 751019, India