Antibiotics or sugar pills? new study questions routine use after dental bone grafts

NCT ID NCT07296302

Not yet recruiting Disease control Sponsor: Agnaldo Rocha de Souza Junior Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares antibiotics (amoxicillin) to a placebo in 150 healthy adults undergoing dental bone grafting after tooth extraction. The goal is to see if antibiotics actually prevent infection or if placebo works just as well. Participants will be monitored for 30 days for infections and 6 months for bone healing.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Amoxicillin (or azithromycin for penicillin allergy)
What this could lead to: If successful, this could show that antibiotics are not needed for routine dental bone grafts, reducing unnecessary drug use and side effects.
What could go wrong: This is a small, early-stage trial with only 150 participants. The results may not apply to all patients, and there is a risk of infection in the placebo group.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALVEOLAR RIDGE AUGMENTATION ANTIBIOTIC PROPHYLAXIS BONE GRAFTING

Contacts and locations

Locations

Universidade Estadual de Montes Claros - Unimontes

Montes Claros, Minas Gerais, 39401-8321, Brazil

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