Antibiotics after tooth extraction: helpful or unnecessary?
NCT ID NCT07694531
First seen Jul 10, 2026 · Last updated Jul 10, 2026
Summary
This trial looks at whether antibiotics are needed after removing a tooth with a periapical abscess (an infection at the root tip). Half of the 176 adult participants receive amoxicillin for 5 days after extraction, while the other half get only pain relievers. A dentist checks the healing of the extraction site on day 5, comparing gum color, bleeding, and signs of infection between the two groups. The goal is to see if skipping antibiotics leads to similar healing, which could help reduce unnecessary antibiotic use.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Amoxicillin 500 mg
- What this could lead to
- If antibiotics prove unnecessary, it could reduce overuse and side effects while maintaining good healing after tooth extraction for abscesses.
- What could go wrong
- This is a small, single-center trial. Results may not apply to larger abscesses or patients with other health conditions. Antibiotic resistance or allergic reactions remain risks.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Oral and Maxillofacial Surgery department in Subbaiah Institute of Dental Sciences
Shimoga, Karnataka, 577201, India
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