Could a common antibiotic spare Last-Resort drugs for ICU lung infections?

NCT ID NCT04276480

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether a common antibiotic (piperacillin-tazobactam) could effectively treat ventilator-associated pneumonia in ICU patients who carry resistant bacteria in their gut. The goal was to see if this approach could reduce the need for stronger, last-resort antibiotics called carbapenems. Only 9 patients were enrolled, and the study measured survival and infection recovery rates.

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Conditions

The condition(s) this trial relates to.

Enterobacteriaceae Infections Pneumonia, Ventilator-Associated

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centre hospitalier de la Côte Basque

    Bayonne, 64100, France

  • Hopital Pellegrin

    Bordeaux, 33000, France

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