Poop pills vs. superbugs: can a fecal transplant clear Drug-Resistant bacteria?
NCT ID NCT05632315
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase II trial tests whether a fecal microbiota transplant (using donor stool) can help eliminate multidrug-resistant organisms (MDROs) from the gut of infected patients. 32 adults with resistant bacterial infections will receive the transplant plus standard antibiotics. The goal is to see if the treatment clears the superbugs and reduces the spread of resistance.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Fecal microbiota transplant (Penn Microbiome Therapy)
- What this could lead to
- If it works, this could offer a way to reduce dangerous antibiotic-resistant bacteria in the gut, potentially lowering infection risk.
- What could go wrong
- This is a small, early-phase trial with only 32 people. The treatment may not work for everyone, and there are risks like infection or side effects from the transplant.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Emory University - Grady Memorial Hospital
Atlanta, Georgia, 30303, United States
-
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
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Washington University
St Louis, Missouri, 63110, United States
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