Lung antibiotic mystery: COVID-19 may block drugs from reaching infection

NCT ID NCT05464680

First seen Nov 19, 2025 · Last updated May 13, 2026 · Updated 16 times

Summary

This study looked at why antibiotics often fail to treat pneumonia in COVID-19 patients on breathing machines. Researchers measured how much of the antibiotic piperacillin reaches the lung fluid in 34 adults with severe lung injury. The goal was to understand if poor drug penetration explains the high rate of repeat infections.

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Contacts and locations

Locations

  • Service Médecine Intensive Réanimation

    Marseille, 13015, France

Conditions

Explore the condition pages connected to this study.