Ventilator pneumonia in COVID-19: antibiotics failing to reach the lungs?

NCT ID NCT05464680

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at why antibiotics often fail to treat pneumonia in COVID-19 patients on ventilators. Researchers measured how much of the antibiotic piperacillin reaches the lungs in 34 adults with severe COVID-19 pneumonia. The goal was to understand if poor lung penetration explains the high rate of repeat infections, which could lead to better dosing strategies.

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Conditions

The condition(s) this trial relates to.

acute respiratory distress syndrome COVID-19

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Service Médecine Intensive Réanimation

    Marseille, 13015, France