New asthma drug shows promise in early trial

NCT ID NCT06748053

Ongoing Disease control Sponsor: GlaxoSmithKline Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new medicine called GSK5784283 for adults with asthma that is not well controlled by their current treatments. The medicine blocks a protein called TSLP that can cause inflammation in the lungs. The trial will involve about 300 people and aims to find the best dose to improve lung function and asthma control.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

GSK5784283 (anti-TSLP antibody)

What this could lead to

If successful, this could lead to a new long-lasting treatment option for people whose asthma is not well controlled with current therapies.

What could go wrong

This is an early Phase 2 dose-finding study, so it is not yet proven to work. The results may not lead to a new treatment, and side effects are still being evaluated.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

asthma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ASTHMA

Contacts and locations

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Locations

GSK Investigational Site

Little Rock, Arkansas, 72205, United States
GSK Investigational Site

Long Beach, California, 90815, United States
GSK Investigational Site

Los Angeles, California, 90025, United States
GSK Investigational Site

Redding, California, 96001, United States
GSK Investigational Site

Riverside, California, 92506, United States
GSK Investigational Site

Sacramento, California, 95817, United States
GSK Investigational Site

San Jose, California, 95117, United States
GSK Investigational Site

Colorado Springs, Colorado, 80923, United States
GSK Investigational Site

Lakewood, Colorado, 80228-1813, United States
GSK Investigational Site

Wheat Ridge, Colorado, 80033, United States
GSK Investigational Site

New Haven, Connecticut, 06511, United States
GSK Investigational Site

Aventura, Florida, 33180, United States
GSK Investigational Site

Hialeah, Florida, 33012, United States
GSK Investigational Site

Lake Worth, Florida, 33460, United States
GSK Investigational Site

Leesburg, Florida, 34748, United States
GSK Investigational Site

Miami, Florida, 33144, United States
GSK Investigational Site

Miami, Florida, 33166, United States
GSK Investigational Site

Miami, Florida, 33172, United States
GSK Investigational Site

Miami, Florida, 33173, United States
GSK Investigational Site

Plantation, Florida, 33324, United States
GSK Investigational Site

Tampa, Florida, 33607, United States
GSK Investigational Site

Skokie, Illinois, 60077, United States
GSK Investigational Site

Shreveport, Louisiana, 71105, United States
GSK Investigational Site

Lathrup Village, Michigan, 48076, United States
GSK Investigational Site

Warren, Michigan, 48088, United States
GSK Investigational Site

Omaha, Nebraska, 68198, United States
GSK Investigational Site

The Bronx, New York, 10461, United States
GSK Investigational Site

Cincinnati, Ohio, 45236, United States
GSK Investigational Site

DuBois, Pennsylvania, 15801, United States
GSK Investigational Site

Philadelphia, Pennsylvania, 19140, United States
GSK Investigational Site

Pittsburgh, Pennsylvania, 15241, United States
GSK Investigational Site

Wyomissing, Pennsylvania, 19610, United States
GSK Investigational Site

Warwick, Rhode Island, 02886, United States
GSK Investigational Site

Greenville, South Carolina, 29607, United States
GSK Investigational Site

Spartanburg, South Carolina, 29303, United States
GSK Investigational Site

Knoxville, Tennessee, 37909, United States
GSK Investigational Site

Boerne, Texas, 78006, United States
GSK Investigational Site

Cypress, Texas, 77429, United States
GSK Investigational Site

Dallas, Texas, 75225, United States
GSK Investigational Site

Houston, Texas, 77058, United States
GSK Investigational Site

Kerrville, Texas, 78028, United States
GSK Investigational Site

McKinney, Texas, 75069, United States
GSK Investigational Site

San Antonio, Texas, 78212, United States
GSK Investigational Site

San Antonio, Texas, 78229, United States
GSK Investigational Site

Sherman, Texas, 75092, United States
GSK Investigational Site

American Fork, Utah, 84003, United States
GSK Investigational Site

Pleasant View, Utah, 84404, United States
GSK Investigational Site

Salt Lake City, Utah, 84117, United States
GSK Investigational Site

South Ogden, Utah, 84405, United States
GSK Investigational Site

Bellingham, Washington, 98225, United States
GSK Investigational Site

Blagoevgrad, 2700, Bulgaria
GSK Investigational Site

Gorna Oryahovitsa, 5100, Bulgaria
GSK Investigational Site

Lovech, 5500, Bulgaria
GSK Investigational Site

Pazardzhik, 4400, Bulgaria
GSK Investigational Site

Plovdiv, 4002, Bulgaria
GSK Investigational Site

Rousse, 7000, Bulgaria
GSK Investigational Site

Rousse, 7002, Bulgaria
GSK Investigational Site

Sofia, 1000, Bulgaria
GSK Investigational Site

Sofia, 1142, Bulgaria
GSK Investigational Site

Sofia, 1233, Bulgaria
GSK Investigational Site

Sofia, 1431, Bulgaria
GSK Investigational Site

Sofia, 1680, Bulgaria
GSK Investigational Site

Stara Zagora, Bulgaria
GSK Investigational Site

Varna, 9000, Bulgaria
GSK Investigational Site

Vratsa, 3000, Bulgaria
GSK Investigational Site

Kelowna, British Columbia, V1Y 4N7, Canada
GSK Investigational Site

Ajax, Ontario, L1S 2J5, Canada
GSK Investigational Site

London, Ontario, N6A 4V2, Canada
GSK Investigational Site

Toronto, Ontario, M5G 1E2, Canada
GSK Investigational Site

Windsor, Ontario, N8X 1T3, Canada
GSK Investigational Site

Trois-Rivières, Quebec, G8T 7A1, Canada
GSK Investigational Site

Brandýs nad Labem, 25001, Czechia
GSK Investigational Site

Mladá Boleslav, 293 01, Czechia
GSK Investigational Site

Teplice, 415 01, Czechia
GSK Investigational Site

Bendorf, 56170, Germany
GSK Investigational Site

Berlin, 10961, Germany
GSK Investigational Site

Berlin, 12203, Germany
GSK Investigational Site

Darmstadt, 64283, Germany
GSK Investigational Site

Frankfurt, 60596, Germany
GSK Investigational Site

Fürstenwalde, 15517, Germany
GSK Investigational Site

Leipzig, 04347, Germany
GSK Investigational Site

Magdeburg, 39120, Germany
GSK Investigational Site

Mainz, 55128, Germany
GSK Investigational Site

München, 81241, Germany
GSK Investigational Site

Neu-Isenburg, 63263, Germany
GSK Investigational Site

Schleswig, 24837, Germany
GSK Investigational Site

Chiba, 275-8580, Japan
GSK Investigational Site

Fukui, 910-8526, Japan
GSK Investigational Site

Fukuoka, 806-8501, Japan
GSK Investigational Site

Fukuoka, 811-1394, Japan
GSK Investigational Site

Fukushima, 960-1295, Japan
GSK Investigational Site

Gifu, 509-6134, Japan
GSK Investigational Site

Hiroshima, 734-8530, Japan
GSK Investigational Site

Hokkaido, 064-0804, Japan
GSK Investigational Site

Hyōgo, 653-0013, Japan
GSK Investigational Site

Kagawa, 762-0043, Japan
GSK Investigational Site

Kanagawa, 236-0051, Japan
GSK Investigational Site

Mie, 515-8544, Japan
GSK Investigational Site

Nagasaki, 852-8501, Japan
GSK Investigational Site

Okayama, 702-8055, Japan
GSK Investigational Site

Osaka, 596-8501, Japan
GSK Investigational Site

Shizuoka, 420-8527, Japan
GSK Investigational Site

Tokyo, 141-8625, Japan
GSK Investigational Site

Tokyo, 162-8655, Japan
GSK Investigational Site

Tokyo, 204-8585, Japan
GSK Investigational Site

Yokohama, 232-0024, Japan
GSK Investigational Site

Bacau, 600252, Romania
GSK Investigational Site

Brasov, 500283, Romania
GSK Investigational Site

Brasov, 500366, Romania
GSK Investigational Site

Bucharest, 050159, Romania
GSK Investigational Site

Cluj-Napoca, 400139, Romania
GSK Investigational Site

Craiova Dolj, 200515, Romania
GSK Investigational Site

Timișoara, 300310, Romania
GSK Investigational Site

Alcorcon Madrid, 28922, Spain
GSK Investigational Site

Barcelona, 08035, Spain
GSK Investigational Site

Barcelona, Spain
GSK Investigational Site

Benalmádena, 29631, Spain
GSK Investigational Site

Jerez de la Frontera, 11407, Spain
GSK Investigational Site

Madrid, 28003, Spain
GSK Investigational Site

Madrid, 28007, Spain
GSK Investigational Site

Madrid, 28031, Spain
GSK Investigational Site

Madrid, 28040, Spain
GSK Investigational Site

Madrid, 28223, Spain
GSK Investigational Site

Málaga, 29010, Spain
GSK Investigational Site

Santander, 39008, Spain
GSK Investigational Site

Seville, 41012, Spain
GSK Investigational Site

Valencia, 46015, Spain
GSK Investigational Site

Valencia, 46017, Spain
GSK Investigational Site

Zaragoza, 50009, Spain
GSK Investigational Site

Bradford, BD9 6RJ, United Kingdom
GSK Investigational Site

London, EC1M 6BQ, United Kingdom
GSK Investigational Site

London, SE1 9RT, United Kingdom
GSK Investigational Site

Newcastle upon Tyne, NE1 4LP, United Kingdom