New drug trial aims to tame debilitating autoimmune disease

NCT ID NCT05925803

Ongoing Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

Summary

This study is testing whether a medication called anifrolumab, given as a weekly injection, can safely help control the symptoms and slow the progression of systemic sclerosis (scleroderma). It will involve about 314 adults with a recent diagnosis of the disease. Participants will receive either the real drug or a placebo for one year, followed by a year where everyone gets the real drug, to see if it improves skin thickening, lung function, and overall health.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

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Scottsdale, Arizona, 85259, United States
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Chula Vista, California, 91910, United States
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Los Angeles, California, 90095, United States
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Orange, California, 92868, United States
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Aurora, Colorado, 80045, United States
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New Haven, Connecticut, 06519, United States
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Washington D.C., District of Columbia, 20007, United States
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Boca Raton, Florida, 33486, United States
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Fort Lauderdale, Florida, 33309, United States
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Gainesville, Florida, 32603, United States
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Jacksonville, Florida, 32216, United States
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Margate, Florida, 33063, United States
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South Miami, Florida, 33143, United States
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Tamarac, Florida, 33321, United States
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Chicago, Illinois, 60611, United States
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Kansas City, Kansas, 66160, United States
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New Orleans, Louisiana, 70121, United States
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Baltimore, Maryland, 21224, United States
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Ann Arbor, Michigan, 48109, United States
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Rochester, Minnesota, 55905, United States
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Babylon, New York, 11702, United States
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New York, New York, 10032, United States
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Cincinnati, Ohio, 45219, United States
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Pittsburgh, Pennsylvania, 15213, United States
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Allen, Texas, 75013, United States
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Houston, Texas, 77030, United States
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Graz, 8036, Austria
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Innsbruck, 6020, Austria
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Vienna, 1090, Austria
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Ghent, B-9000, Belgium
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Leuven, 3000, Belgium
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Calgary, Alberta, T2N 4Z6, Canada
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Toronto, Ontario, M5T 3L9, Canada
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Montreal, Quebec, H3T 1E2, Canada
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Montreal, Quebec, H4J 1C5, Canada
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Québec, G1V 3M7, Canada
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Beijing, 100191, China
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Beijing, CN-100730, China
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Guangzhou, 510100, China
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Guangzhou, 510530, China
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Hangzhou, 310014, China
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Lanzhou, 730000, China
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Shanghai, 200032, China
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Shanghai, 201210, China
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Tianjin, 300050, China
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Bordeaux, 33076, France
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Brest, 29609, France
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Paris, 75020, France
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Paris, 75679, France
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Rennes, 35033, France
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Strasbourg, 67098, France
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Toulouse, 31059, France
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Freiburg im Breisgau, 79106, Germany
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Mainz, 55131, Germany
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Minden, 32429, Germany
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Münster, 48149, Germany
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Tübingen, 72076, Germany
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Budapest, 1023, Hungary
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Budapest, 1027, Hungary
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Budapest, 1138, Hungary
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Debrecen, 4032, Hungary
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Pécs, 7632, Hungary
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Szeged, 6725, Hungary
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Ahmedabad, 380006, India
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Delhi, 110060, India
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Gurugram, 122001, India
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Hyderabad, 500082, India
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Kolkata, 700020, India
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Mumbai, 400053, India
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Mysuru, 570004, India
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New Delhi, 11029, India
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Pune, 411001, India
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Secunderabad, 500003, India
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Afula, 18101, Israel
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Haifa, 31048, Israel
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Haifa, 31096, Israel
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Jerusalem, 00000, Israel
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Kfar Saba, 4428164, Israel
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Ramat Gan, 52621, Israel
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Ancona, 60126, Italy
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Brescia, 25123, Italy
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Cona, 44124, Italy
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Milan, 20122, Italy
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Padua, 35128, Italy
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Roma, 00128, Italy
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Roma, 00168, Italy
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Roma, 161, Italy
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Bunkyō City, 113-8603, Japan
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Fukuoka, 812-8582, Japan
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Iruma-Gun, 350-0495, Japan
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Kanazawa, 920-8641, Japan
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Maebashi, 371-8511, Japan
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Nagasaki, 852-8501, Japan
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Nagoya, 457-0866, Japan
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Sapporo, 060-8638, Japan
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Sendai, 980-8574, Japan
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Shinjuku-ku, 160-8582, Japan
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Shinjuku-ku, 162-8666, Japan
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Suita-shi, 565-0871, Japan
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Takatsuki-shi, 569-8686, Japan
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Toyoake-shi, 470-1192, Japan
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Yokohama, 236-0004, Japan
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Kuala Lumpur, 59100, Malaysia
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Kuching, 93586, Malaysia
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Seremban, 70300, Malaysia
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Chihuahua City, 31000, Mexico
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Guadalajara, 44158, Mexico
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Guadalajara, 44650, Mexico
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Mexico City, 06700, Mexico
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San Luis Potosí City, 78213, Mexico
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San Luis Potosí City, 78250, Mexico
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Groningen, 9713 GZ, Netherlands
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Bydgoszcz, 85-168, Poland
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Krakow, 30-002, Poland
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Krakow, 30-721, Poland
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Lodz, 90-549, Poland
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Sosnowiec, 41-200, Poland
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Warsaw, 00-874, Poland
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Bucharest, 011172, Romania
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Bucharest, 020475, Romania
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Cluj-Napoca, 400006, Romania
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Iași, 700661, Romania
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Parktown, 2193, South Africa
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Pretoria, South Africa
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Busan, 49241, South Korea
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Seoul, 03080, South Korea
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Seoul, 04401, South Korea
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Seoul, 04763, South Korea
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Seoul, 137-701, South Korea
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A Coruña, 15006, Spain
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Barcelona, 08003, Spain
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Barcelona, 08041, Spain
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Madrid, 28041, Spain
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Málaga, 29009, Spain
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Valencia, 46017, Spain
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Valencia, 46026, Spain
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Ankara, 06100, Turkey (Türkiye)
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Ankara, 06230, Turkey (Türkiye)
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Antalya, 07059, Turkey (Türkiye)
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Center, 23200, Turkey (Türkiye)
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Kazımkarabekir, 01230, Turkey (Türkiye)
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Kocaeli, 41380, Turkey (Türkiye)
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Cannock, WS11 2XY, United Kingdom
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Leeds, LS7 4SA, United Kingdom
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London, NW3 2QG, United Kingdom
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Sheffield, S10 2JF, United Kingdom
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Hanoi, 10000, Vietnam
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Hà Nội, 100000, Vietnam
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Ho Chi Minh City, 700000, Vietnam
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Ho Chi Minh City, 70000, Vietnam
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Hochiminh, 70000, Vietnam

Conditions

Explore the condition pages connected to this study.

SCLERODERMA SYSTEMIC SCLEROSIS