New drug trial aims to tame dangerous kidney disease in lupus patients

NCT ID NCT05138133

Ongoing Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

Summary

This study is testing whether adding the drug anifrolumab to standard treatment helps adults with active lupus nephritis, a serious kidney disease caused by lupus. About 360 participants will receive either anifrolumab or a placebo (dummy drug) for 76 weeks, followed by an optional extension period. The main goal is to see if the drug leads to a better kidney response and allows patients to reduce their steroid use.

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Contacts and locations

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Locations

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Glendale, Arizona, 85306, United States
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La Palma, California, 90623, United States
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Los Angeles, California, 90095, United States
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Upland, California, 91786, United States
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Plantation, Florida, 33324, United States
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Atlanta, Georgia, 30308, United States
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Louisville, Kentucky, 40202, United States
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Summit, New Jersey, 07901, United States
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Manhasset, New York, 11030, United States
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New York, New York, 10016, United States
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Winston-Salem, North Carolina, 27157, United States
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Middleburg Heights, Ohio, 44130, United States
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Colleyville, Texas, 76034, United States
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Edinburg, Texas, 78539, United States
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El Paso, Texas, 79902, United States
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Houston, Texas, 77054, United States
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CABA, C1425EOE, Argentina
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Ciudad de Buenos Aires, C1015ABO, Argentina
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La Plata, 1900, Argentina
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Rosario, S2000PBJ, Argentina
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San Juan, 5400, Argentina
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Brussels, 1200, Belgium
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Leuven, 3000, Belgium
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Liège, 4000, Belgium
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Belo Horizonte, 30130 100, Brazil
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Campinas, 13087-567, Brazil
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Cuiabá, 78020-500, Brazil
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Maringá, 87060-040, Brazil
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Porto Alegre, 90035-903, Brazil
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Recife, 50740-465, Brazil
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Salvador, 40150-150, Brazil
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São José do Rio Preto, 15090-000, Brazil
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São Paulo, 04014-002, Brazil
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São Paulo, 04036-002, Brazil
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São Paulo, 05403-9000, Brazil
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Plovdiv, 4002, Bulgaria
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Sofia, 1431, Bulgaria
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Beijing, 100034, China
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Beijing, 100044, China
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Bengbu, 233004, China
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Chengdu, 610072, China
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Guangzhou, 510530, China
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Haikou, 570311, China
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Hangzhou, 310009, China
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Jinan, 250021, China
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Jining, 272011, China
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Nanchang, 330006, China
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Nanjing, 210009, China
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Nanjing, 210029, China
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Nanning, 530021, China
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Shanghai, 200025, China
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Shanghai, 200040, China
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Shengyang, 110004, China
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Shenzhen, 518036, China
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Shijiazhuang, 050001, China
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Tianjin, 300201, China
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Wuhan, 430060, China
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Wuxi, 214023, China
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Xi'an, 710061, China
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Zhengzhou, 450000, China
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Barranquilla, 080020, Colombia
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Medellín, 050010, Colombia
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Medellín, 050025, Colombia
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Aurillac, 15002, France
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Bordeaux, 33076, France
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Marseille, 13005, France
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Paris, 75013, France
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Paris, 75018, France
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Paris, 75679, France
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Strasbourg, 67098, France
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Toulouse, 31059, France
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Cologne, 50937, Germany
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Dresden, 1307, Germany
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Hanover, 30625, Germany
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Heidelberg, 69120, Germany
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Kirchheim, 73230, Germany
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Mainz Am Rhein, 55131, Germany
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Budapest, 1085, Hungary
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Budapest, 1097, Hungary
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Debrecen, 4032, Hungary
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Ahmedabad, 380005, India
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Ahmedabad, 382421, India
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Dehradun, 248001, India
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Delhi, 110029, India
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Hyderabad, 500082, India
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Kolkata, 700020, India
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Nadiād, 387001, India
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Pune, 411001, India
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Secunderabad, 500003, India
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Vijayawada, 522002, India
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Visakapatnam, 530013, India
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Ancona, 60126, Italy
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Bologna, 40138, Italy
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Cona, 44124, Italy
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Eboli, 84025, Italy
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Padua, 35128, Italy
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Roma, 00161, Italy
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Bunkyō City, 113-8655, Japan
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Chiba, 260-8712, Japan
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Hiroshima, 734-8551, Japan
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Kita-gun, 761-0793, Japan
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Kitakyushu-shi, 807-8555, Japan
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Matsumoto-shi, 390-8621, Japan
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Nagasaki, 852-8501, Japan
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Okayama, 700-8558, Japan
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Ono, 675-1392, Japan
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Sagamihara-shi, 252-0375, Japan
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Sendai, 980-0872, Japan
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Shinagawa-ku, 142-0054, Japan
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Shinjuku-ku, 160-8582, Japan
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Shinjuku-ku, 162-8655, Japan
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Shinjuku-ku, 162-8666, Japan
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Toyoake-shi, 470-1192, Japan
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Batu Caves, 68100, Malaysia
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Ipoh, 30450, Malaysia
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Kajang, 43000, Malaysia
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Kuala Lumpur, 59100, Malaysia
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Kuantan, 25100, Malaysia
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Taiping, 34000, Malaysia
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Chihuahua City, 31000, Mexico
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Guadalajara, 44160, Mexico
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Guadalajara, 44650, Mexico
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México, 06726, Mexico
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México, 14080, Mexico
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San Luis Potosí City, 78290, Mexico
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Amsterdam, 1105 AZ, Netherlands
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Lima, 15023, Peru
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Lima, 15046, Peru
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Lima, 15102, Peru
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Lima, L34, Peru
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Lima, LIMA 27, Peru
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Lima, LIMA 29, Peru
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Lodz, 92-213, Poland
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Olsztyn, 10-561, Poland
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Opole, 46-020, Poland
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Poznan, 60-355, Poland
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Poznan, 61-545, Poland
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Rzeszów, 35-301, Poland
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Warsaw, 02-006, Poland
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Caguas, 00725, Puerto Rico
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Moscow, 115522, Russia
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Kaohsiung City, 833, Taiwan
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New Taipei City, 220, Taiwan
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Taichung, 40447, Taiwan
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Taichung, 40705, Taiwan
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Taipei, 11217, Taiwan
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Taipei, 114, Taiwan
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Taipei, 235, Taiwan
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Bangkok, 10220, Thailand
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Bangkok, 10330, Thailand
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Hat Yai, 90110, Thailand
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Muang, 50200, Thailand
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Ratchathewi, 10400, Thailand
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Adapazarı, 54290, Turkey (Türkiye)
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Ankara, 06100, Turkey (Türkiye)
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Ankara, Turkey (Türkiye)
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Istanbul, 34865, Turkey (Türkiye)
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Istanbul, Turkey (Türkiye)
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Izmir, 35965, Turkey (Türkiye)
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Kahramanmaraş, 46100, Turkey (Türkiye)
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Kayseri, 38039, Turkey (Türkiye)
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Kocaeli, 41380, Turkey (Türkiye)
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Hanoi, 100000, Vietnam
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Hanoi, 10000, Vietnam
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Hà Nội, 100000, Vietnam
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Ho Chi Minh City, 700000, Vietnam
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Hochiminh, 70000, Vietnam

Conditions

Explore the condition pages connected to this study.

LUPUS NEPHRITIS