Could a natural hormone protect aging hearts?

NCT ID NCT05301192

Recruiting now Knowledge-focused Sponsor: Milton S. Hershey Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This early-phase study tests whether angiotensin-(1-7), a natural hormone, can improve blood vessel function and lower blood pressure in healthy adults aged 65-80. Researchers will measure nerve activity and blood vessel responses during a short infusion of the hormone compared to a placebo. The goal is to understand if this hormone could reduce cardiovascular risk in aging.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Angiotensin-(1-7)
What this could lead to: If it works, this could point toward a new way to reduce cardiovascular risk in older adults.
What could go wrong: This is a very early, small study (26 people) testing a short-term infusion, so it may not lead to a practical treatment. Results may not apply to people with high blood pressure or other health conditions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AGING

Contacts and locations

Locations

Penn State Milton S. Hershey Medical Center
RECRUITING

Hershey, Pennsylvania, 17033, United States

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