Could a natural hormone protect aging hearts?

NCT ID NCT05301192

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This early-phase study tests whether angiotensin-(1-7), a natural hormone, can improve blood vessel function and lower blood pressure in healthy adults aged 65-80. Researchers will measure nerve activity and blood vessel responses during a short infusion of the hormone compared to a placebo. The goal is to understand if this hormone could reduce cardiovascular risk in aging.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Angiotensin-(1-7)

What this could lead to

If it works, this could point toward a new way to reduce cardiovascular risk in older adults.

What could go wrong

This is a very early, small study (26 people) testing a short-term infusion, so it may not lead to a practical treatment. Results may not apply to people with high blood pressure or other health conditions.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Penn State Milton S. Hershey Medical Center

    RECRUITING

    Hershey, Pennsylvania, 17033, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact

    Contact