New stent and shorter blood thinners could make heart treatment safer

NCT ID NCT05952206

Ongoing Disease control Sponsor: iVascular S.L.U. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 3 trial tests two things at once in 2312 people with coronary artery disease: a new drug-coated stent (Angiolite) versus a standard stent, and a shorter course of blood thinners versus the usual longer course. The goal is to see if the new stent works as well and if shorter blood thinners cause less bleeding without increasing heart attacks or strokes. Participants are randomly assigned to one of four groups and followed for 12 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: sirolimus-eluting stent (Angiolite) and abbreviated dual antiplatelet therapy (shorter course of blood thinners)
What this could lead to: If successful, this could show that a newer stent works just as well as current ones, and that a shorter course of blood thinners can lower bleeding risk without raising heart attack or stroke risk.
What could go wrong: This is a phase 3 trial, but results may not apply to all patients. The shorter blood thinner course might increase the risk of stent clotting or heart attacks in some people.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CORONARY ARTERY DISEASE

Contacts and locations

Locations

Az Delta

Roeselare, Belgium
Az Turnhout

Turnhout, Belgium
CHC Montlégia

Liège, Belgium
CHU Marie Curie

Charleroi, Belgium
Chu Ambroise Pare

Mons, Belgium
Chu Lille

Lille, France
Chu Toulouse

Toulouse, France
Complejo Hospitalario Torrecárdenas

Almería, Spain
Complejo Hospitalario Universitario A Coruña

A Coruña, Spain
Hospital Clínic de Barcelona

Barcelona, Spain
Hospital Clínico Universitario Virgen de La Arrixaca

Murcia, Spain
Hospital Clínico Universitario de Santiago

Santiago de Compostela, Spain
Hospital Clínico Universitario de Valencia

Valencia, Spain
Hospital Clínico Universitario de Valladolid

Valladolid, Spain
Hospital Germans Trias I Pujol

Barcelona, Spain
Hospital San Pedro de Alcantara

Cáceres, Spain
Hospital Universitari Son Espases

Palma de Mallorca, Spain
Hospital Universitario 12 de Octubre

Madrid, Spain
Hospital Universitario Jerez de La Frontera

Jerez de la Frontera, Spain
Hospital Universitario Juan Ramón Jiménez

Huelva, Spain
Hospital Universitario Marqués de Valdecilla

Santander, Spain
Hospital Universitario Miguel Servet

Zaragoza, Spain
Hospital Universitario Puerta de Hierro

Madrid, Spain
Hospital Universitario Regional de Málaga

Málaga, Spain
Hospital Universitario Vall D'Hebrón

Barcelona, Spain
Hospital Universitario Virgen de La Victoria

Málaga, Spain
Hospital Universitario Y Politécnico La Fe

Valencia, Spain
Hospital Universitario de Bellvitge

Barcelona, Spain
Hospital Universitario de Gran Canaria Doctor Negrín

Las Palmas de Gran Canaria, Spain
Hospital Universitario de León

León, Spain
Hospital de La Citadelle

Liège, Belgium
Hospital de La Santa Creu I Sant Pau

Barcelona, Spain
Hospital de Navarra

Pamplona, Spain
Hospital Álvaro Cunqueiro

Vigo, Spain
IMELDA

Bonheiden, Belgium
Icps Massy

Massy, France
Ipcs Quincy

Quincy-sous-Sénart, France
ZOL GENK

Genk, Belgium

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