Which anesthesia is safer for aging brains? new study investigates
NCT ID NCT06353516
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at how two different anesthesia methods—intravenous propofol versus inhaled sevoflurane gas—affect the brain's protective barrier and the risk of confusion after surgery in 154 older adults (age 60+). Researchers measured a protein in the blood that indicates brain barrier leakage and tracked whether patients developed delirium or cognitive problems. The goal is to find out if one type of anesthesia is better at protecting the brain during surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Propofol (intravenous) and sevoflurane (inhaled gas)
What this could lead to
If one anesthesia type is found to better protect the brain's barrier, it could help reduce confusion and memory problems after surgery in older adults.
What could go wrong
This is a small, completed study measuring blood markers, not a direct test of long-term outcomes. Results may not apply to all surgeries or patients.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for POSTOPERATIVE COGNITIVE DYSFUNCTION are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Chung-Ang University Gwangmyeong Hospital
Gwangmyeong, Gyeonggi-do, 14353, South Korea