Ancient wheat may be gentler on sensitive stomachs
NCT ID NCT06191432
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether an ancient type of wheat (Triticum monococcum) causes fewer stomach and other symptoms than modern wheat in people with non-celiac wheat sensitivity. Sixty-eight adults who follow a wheat-free diet will eat both types of wheat in a blinded crossover design. Researchers will track symptoms, quality of life, and look for blood markers that could help diagnose the condition.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Triticum monococcum flour (an ancient type of wheat)
- What this could lead to
- If this ancient wheat is better tolerated, it could offer a dietary option for people with non-celiac wheat sensitivity and help identify blood markers for diagnosis.
- What could go wrong
- This is a small, early-stage study (68 people) testing short-term exposure only. Results may not apply to everyone, and participants could still react to the ancient wheat.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University Hospital of Palermo
RECRUITINGPalermo, Sicily, 90127, Italy
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