New study aims to improve anal cancer screening for those at highest risk

NCT ID NCT06628570

Recruiting now Diagnosis Sponsor: Lisa Flowers Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looks at different screening methods to find anal precancer in people at high risk, such as those with weakened immune systems or a history of certain genital cancers. Researchers will compare tests like high-resolution anoscopy, HPV testing, and cell samples to see which works best. The goal is to improve early detection and understand factors linked to the disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to better, more accurate screening tests for anal precancer in high-risk people, helping catch it early.
What could go wrong: This is an early-stage study focused on comparing screening methods, not testing a treatment. Results may not change current practice immediately.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

anal squamous cell carcinoma neoplasm squamous cell intraepithelial neoplasia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

Grady Memorial Hospital
RECRUITING

Atlanta, Georgia, 30303, United States
The Ponce Center
RECRUITING

Atlanta, Georgia, 30308, United States
University of Miami Miller School of Medicine-Sylvester Cancer Center
RECRUITING

Miami, Florida, 33136, United States
University of Miami School of Medicine at Jackson Memorial Hospital (JMH)
RECRUITING

Miami, Florida, 33136, United States

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