Gene therapy injection aims to quiet seizures in Drug-Resistant epilepsy
NCT ID NCT06063850
First seen Nov 01, 2025 · Last updated May 09, 2026 · Updated 28 times
Summary
This early-stage study tests a new gene therapy called AMT-260 in 12 adults with a specific type of epilepsy (mesial temporal lobe epilepsy) that does not respond to standard medications. The treatment is delivered directly into the brain using MRI guidance. The main goals are to check safety and see if it can reduce seizure frequency over one year.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Allegheny Health Network
RECRUITINGPittsburgh, Pennsylvania, 15212, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Baylor Scott & White Medical Center
RECRUITINGAustin, Texas, 78735, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Cleveland Clinic
RECRUITINGCleveland, Ohio, 44195, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Corewell Health
RECRUITINGGrand Rapids, Michigan, 49503, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Dartmouth Hitchcock Medical Center
RECRUITINGLebanon, New Hampshire, 03756, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hospital of the University of Pennsylvania
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
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Johns Hopkins School of Medicine
RECRUITINGBaltimore, Maryland, 21287, United States
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Kansas University Medical Center
RECRUITINGKansas City, Kansas, 66160, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02114, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Mayo Clinic Arizona
RECRUITINGPhoenix, Arizona, 85054, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Mayo Clinic Florida
RECRUITINGJacksonville, Florida, 32224, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Medical College of Wisconsin
RECRUITINGMilwaukee, Wisconsin, 53226, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Midatlantic Epilepsy and Sleep Center
RECRUITINGBethesda, Maryland, 20817, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Northeast Regional Epilepsy Group
RECRUITINGHackensack, New Jersey, 07601, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Ohio State University
RECRUITINGColumbus, Ohio, 43210, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Robert Wood Johnson Hospital
RECRUITINGNew Brunswick, New Jersey, 08901, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Stanford University
RECRUITINGPalo Alto, California, 94304, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Alabama at Birmingham
RECRUITINGBirmingham, Alabama, 35294-0021, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Conditions
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