Stroke prevention device tested in chinese heart patients

NCT ID NCT06189365

Terminated Disease control Sponsor: Abbott Medical Devices Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Aug 14, 2026 · Updated 4 times

Summary

This study tested a device called the Amplatzer Amulet, which is implanted to close a part of the heart and reduce stroke risk in people with non-valvular atrial fibrillation who cannot take blood thinners. The study enrolled 50 participants in China and tracked safety and effectiveness for up to 2 years. However, the study was terminated early, so the full results are not available.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Amplatzer Amulet LAA occluder device
What this could lead to: If successful, this device could offer a safe alternative to long-term blood thinners for preventing stroke in people with atrial fibrillation.
What could go wrong: The study was terminated early with only 50 participants, so results are limited. Risks include serious complications like stroke, device-related infections, or device movement.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NON-VALVULAR ATRIAL FIBRILLATION

Contacts and locations

Locations

The Third Xiangya Hospital of Central South University

Changsha, Hunan, 410013, China
University of Hong Kong-Shenzhen Hospital

Shenzhen, Guangdong, 518009, China
Wuhan Asia Heart Hospital

Wuhan, Hubei, 430022, China
Xiangya Hospital Zhuzhou Central South University

Zhuzhou, Hunan, 412007, China
Xianyang Hospital Of Yan'an University

Xianyang, Shaanxi, China

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