Stroke prevention device tested in chinese heart patients

NCT ID NCT06189365

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a device called the Amplatzer Amulet, which is implanted to close a part of the heart and reduce stroke risk in people with non-valvular atrial fibrillation who cannot take blood thinners. The study enrolled 50 participants in China and tracked safety and effectiveness for up to 2 years. However, the study was terminated early, so the full results are not available.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Amplatzer Amulet LAA occluder device

What this could lead to

If successful, this device could offer a safe alternative to long-term blood thinners for preventing stroke in people with atrial fibrillation.

What could go wrong

The study was terminated early with only 50 participants, so results are limited. Risks include serious complications like stroke, device-related infections, or device movement.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

atrial fibrillation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The Third Xiangya Hospital of Central South University

    Changsha, Hunan, 410013, China

  • University of Hong Kong-Shenzhen Hospital

    Shenzhen, Guangdong, 518009, China

  • Wuhan Asia Heart Hospital

    Wuhan, Hubei, 430022, China

  • Xiangya Hospital Zhuzhou Central South University

    Zhuzhou, Hunan, 412007, China

  • Xianyang Hospital Of Yan'an University

    Xianyang, Shaanxi, China