New combo therapy aims to shrink tough head and neck cancers

NCT ID NCT07062354

First seen Feb 06, 2026 · Last updated May 16, 2026 · Updated 16 times

Summary

This study tests a combination of the targeted drug amivantamab plus two chemotherapy drugs (carboplatin and paclitaxel) in 50 adults with head and neck cancer that has come back or spread. Participants have already tried a PD-1 inhibitor. The goal is to see if the combination can shrink tumors and control the disease. The study is currently enrolling by invitation.

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Contacts and locations

Locations

  • University of Arizona Cancer Center

    Tucson, Arizona, 85719, United States

  • University of Michigan Rogel Cancer Center

    Ann Arbor, Michigan, 48109, United States

  • University of Nebraska Medical Center

    Omaha, Nebraska, 68198, United States

Conditions

Explore the condition pages connected to this study.