Study checks if antibiotic dosing hits the mark in ICU sepsis patients

NCT ID NCT02888470

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study examines whether intensive care unit (ICU) patients being treated for sepsis receive aminoglycoside antibiotics at doses that achieve the recommended peak concentration in the blood. Researchers will measure drug levels after the first and later doses in about 90 adults. The goal is to understand how often current dosing practices hit the target, which could help improve antibiotic therapy in critically ill patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

aminoglycoside antibiotics

What this could lead to

If the study finds that current dosing often misses the target, it could lead to better dosing guidelines for ICU patients with sepsis.

What could go wrong

This is an observational study that only measures current practice, not a test of a new treatment. It cannot prove that changing doses improves outcomes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

infectious disease with sepsis Sepsis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CHU de Nîmes

    Nîmes, Gard, 30029, France