New PET tracer aims to spot Alzheimer's tau tangles
NCT ID NCT05542953
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This completed Phase 3 study tested whether a radioactive tracer called [18F]APN-1607 can help detect Alzheimer's disease by lighting up tau tangles in the brain during a PET scan. Researchers compared brain scans of 230 people with Alzheimer's, mild cognitive impairment, and healthy volunteers. The goal was to see if the tracer's pattern differs between groups, which could improve diagnosis.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
[18F]APN-1607 (a radioactive tracer for PET scans)
What this could lead to
If successful, this could lead to a better way to diagnose Alzheimer's disease earlier and more accurately using a brain scan.
What could go wrong
This is a diagnostic study, not a treatment. The tracer may not clearly distinguish between Alzheimer's and other dementias, and results may not change patient outcomes.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for HEALTHY VOLUNTEERS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Union Hospital Tongji Medical College Huazhong University of Science and Technology
Wuhan, Hubei, 430000, China