Breath of hope: drug and oxygen combo tested for ALS breathing
NCT ID NCT05377424
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a drug called istradefylline, combined with short periods of breathing low-oxygen air (acute intermittent hypoxia), can improve breathing in people with ALS. About 40 adults with ALS and healthy volunteers will take part. The goal is to see if this combination is safe and helps the diaphragm work better, making breathing easier.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Clinical and Translational Research Building
Gainesville, Florida, 32610, United States
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UF Health Jacksonville
Jacksonville, Florida, 32209, United States
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