Could a Parkinson's drug and low-oxygen breathing boost lung power in ALS?
NCT ID NCT05377424
First seen Feb 24, 2026 · Last updated May 16, 2026 · Updated 14 times
Summary
This study tests whether a medication called istradefylline, combined with short periods of breathing air with less oxygen (acute intermittent hypoxia), can improve breathing in people with ALS. About 40 adults with ALS and healthy volunteers will take part. The goal is to see if this combination is safe and helps strengthen breathing muscles.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Clinical and Translational Research Building
Gainesville, Florida, 32610, United States
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UF Health Jacksonville
Jacksonville, Florida, 32209, United States
Conditions
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