ALS biomarker hunt aims to boost failed drug trials

NCT ID NCT02360891

Completed Knowledge-focused Sponsor: University Hospital, Lille Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study of 500 people with ALS (Lou Gehrig's disease) aimed to find biological signs, or biomarkers, that can predict how the disease will progress. Researchers collected clinical, imaging, and lab data to better understand different forms of ALS. The goal is to help future drug trials select the right patients and improve chances of success.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help identify which patients might respond to certain treatments, making future ALS drug trials more effective.
What could go wrong: This is an observational study, not a treatment trial. It may not directly lead to new therapies, and the biomarkers found may not be reliable enough to change clinical practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

amyotrophic lateral sclerosis motor neuron disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AMYOTROPHIC LATERAL SCLEROSIS MOTOR NEURON DISEASE

Contacts and locations

Locations

AP-HM,Hôpital de la Timone

Marseille, France
CHRU, Hôpital Salengro

Lille, France
CHU Bretonneau

Tours, France
CHU Cote de Nacre

Caen, France
CHU Gabriel Montpied

Clermont-Ferrand, France
CHU Pontchaillou

Angers, France
Centre Hospitalier

Saint-Brieuc, France
Hôpital Dupuytren

Limoges, France
Hôpital Gui de Chauliac

Montpellier, France
Hôpital La Pitié (AP-HP)

Paris, France
Hôpital Neurologique Pierre Wertheimer

Lyon, France
Hôpital Nord

Saint-Etienne, France
Hôpital de l'Archet 1, CHU

Nice, France

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