ALS biomarker hunt aims to boost failed drug trials

NCT ID NCT02360891

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study of 500 people with ALS (Lou Gehrig's disease) aimed to find biological signs, or biomarkers, that can predict how the disease will progress. Researchers collected clinical, imaging, and lab data to better understand different forms of ALS. The goal is to help future drug trials select the right patients and improve chances of success.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could help identify which patients might respond to certain treatments, making future ALS drug trials more effective.

What could go wrong

This is an observational study, not a treatment trial. It may not directly lead to new therapies, and the biomarkers found may not be reliable enough to change clinical practice.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

amyotrophic lateral sclerosis motor neuron disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • AP-HM,Hôpital de la Timone

    Marseille, France

  • CHRU, Hôpital Salengro

    Lille, France

  • CHU Bretonneau

    Tours, France

  • CHU Cote de Nacre

    Caen, France

  • CHU Gabriel Montpied

    Clermont-Ferrand, France

  • CHU Pontchaillou

    Angers, France

  • Centre Hospitalier

    Saint-Brieuc, France

  • Hôpital Dupuytren

    Limoges, France

  • Hôpital Gui de Chauliac

    Montpellier, France

  • Hôpital La Pitié (AP-HP)

    Paris, France

  • Hôpital Neurologique Pierre Wertheimer

    Lyon, France

  • Hôpital Nord

    Saint-Etienne, France

  • Hôpital de l'Archet 1, CHU

    Nice, France