Could a 6-month IV drip help severe heart failure patients avoid death or transplant?

NCT ID NCT00610051

First seen Jan 11, 2026 · Last updated May 23, 2026 · Updated 19 times

Summary

This Phase 3 study tests a continuous 6-month infusion of alprostadil (ALP-1) versus placebo in 600 adults with advanced heart failure and reduced ejection fraction. The goal is to see if the drug can delay death, need for heart transplant, or other major heart events. Participants must have severe symptoms (NYHA class IIIb or IV) and specific lab markers.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Medical university Vienna

    Vienna, Austria

Conditions

Explore the condition pages connected to this study.