Simple stool test could spot gut inflammation without a scope

NCT ID NCT06810518

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing a new stool test that measures calprotectin, a protein that signals inflammation in the gut. The goal is to see if the test can help doctors diagnose Crohn's disease or ulcerative colitis and tell them apart from irritable bowel syndrome. About 220 adults with gut symptoms will provide stool samples, which will be compared to results from colonoscopy. If accurate, this test could offer a simpler, less invasive way to diagnose inflammatory bowel disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ALPCO Calprotectin CLIA assay (a stool test device)

What this could lead to

If successful, this test could help doctors quickly and accurately tell the difference between inflammatory bowel disease and irritable bowel syndrome, reducing the need for invasive procedures.

What could go wrong

This is an early-stage diagnostic study, not a treatment trial. The test may not be accurate enough to replace current methods, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Crohn disease inflammatory bowel disease irritable bowel syndrome ulcerative colitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • ALPCO

    NOT_YET_RECRUITING

    Salem, New Hampshire, 03079, United States

  • Gastro Intestinal Research Institute of Northern Ohio,

    RECRUITING

    Westlake, Ohio, 44145, United States

  • Med-Care Research Corp

    RECRUITING

    Miami, Florida, 33125, United States