New immune therapy takes on advanced liver cancer

NCT ID NCT05033522

First seen Jun 24, 2026 · Last updated Jun 24, 2026

Summary

This study tests an experimental immunotherapy called AlloStim against standard treatments (sorafenib, lenvatinib, or chemotherapy) in 150 Asian adults with advanced liver cancer that cannot be treated with surgery or local therapies. Participants are randomly assigned to receive either AlloStim or a standard drug. The main goal is to see if AlloStim helps people live longer and improves their quality of life.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Chiangmai University

    Chiang Mai, Thailand

  • Columbia Asia Bukit Rimau

    Shah Alam, Selangor, 40460, Malaysia

  • Naresuan University Hospital

    Phitsanulok, Tha Pho, 65000, Thailand

  • Prince of Songkla University (Songklanagarind Hospital)

    Hat Yai, Changwat Songkhla, 90110, Thailand

  • Siriraj Hospital

    Bangkok Noi, Bangkok, 10700, Thailand

  • Songklanagarind Hospital

    Khon Kaen, Thailand

  • Sultan Ismail Hospital

    Johor Bahru, Johor, 81100, Malaysia

  • Sultanah Bahiyah Hospital

    Alor Star, Kedah, 05460, Malaysia

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

AlloStim immunotherapy (a type of immune cell therapy)

What this could lead to

If it works, this could offer a new treatment option for advanced liver cancer that may improve survival and quality of life.

What could go wrong

The trial is currently suspended, and it is still in early-to-mid stages. The immunotherapy may not work better than existing drugs, and side effects are possible.

Conditions

The condition(s) this trial relates to.

hepatocellular carcinoma Liver Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.