New immunotherapy aims to fight advanced liver cancer

NCT ID NCT05033522

Terminated Disease control Sponsor: Mirror Biologics, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests an immunotherapy called AlloStim against standard treatments (sorafenib, lenvatinib, or chemotherapy) in 150 Asian adults with advanced liver cancer that cannot be treated with surgery or local therapies. Participants are randomly assigned to receive either AlloStim or a standard drug. The main goal is to see if AlloStim improves overall survival and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: AlloStim immunotherapy
What this could lead to: If it works, this could offer a new immunotherapy option for advanced liver cancer patients who have few alternatives.
What could go wrong: The trial is suspended, so results are uncertain. It is still early and may not show a survival benefit over existing drugs.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

hepatocellular carcinoma Liver Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEPATOCELLULAR CARCINOMA

Contacts and locations

Locations

Chiangmai University

Chiang Mai, Thailand
Columbia Asia Bukit Rimau

Shah Alam, Selangor, 40460, Malaysia
Naresuan University Hospital

Phitsanulok, Tha Pho, 65000, Thailand
Prince of Songkla University (Songklanagarind Hospital)

Hat Yai, Changwat Songkhla, 90110, Thailand
Siriraj Hospital

Bangkok Noi, Bangkok, 10700, Thailand
Songklanagarind Hospital

Khon Kaen, Thailand
Sultan Ismail Hospital

Johor Bahru, Johor, 81100, Malaysia
Sultanah Bahiyah Hospital

Alor Star, Kedah, 05460, Malaysia

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