New hope for tough lung cancer: targeted drug alisertib under study

NCT ID NCT06095505

Recruiting now Disease control Sponsor: Puma Biotechnology, Inc. Source: ClinicalTrials.gov ↗

First seen Sep 30, 2025 · Last updated May 14, 2026 · Updated 26 times

Summary

This study tests an experimental drug called alisertib in people with advanced small cell lung cancer whose disease has worsened after standard treatments. About 80 adults will receive alisertib alone to see if it can shrink tumors or slow the cancer. Researchers will also look for specific markers to identify who might benefit most.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Show contact details

Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Beth Israel Deaconess Medical Center
RECRUITING

Boston, Massachusetts, 02215, United States
Clermont Oncology Center
RECRUITING

Clermont, Florida, 64711, United States
Cleveland Clinic
ACTIVE_NOT_RECRUITING

Cleveland, Ohio, 44195, United States
Dana Farber Cancer Institute
RECRUITING

Boston, Massachusetts, 02215, United States
Georgetown Lombardi Cancer Center
RECRUITING

Washington D.C., District of Columbia, 20057, United States
Henry Ford Hospital
RECRUITING

Detroit, Michigan, 48202, United States
Illinois Cancer Specialists
RECRUITING

Niles, Illinois, 60714, United States
Indiana University Melvin and Bren Simon Comprehensive Cancer Center
RECRUITING

Indianapolis, Indiana, 46202, United States
Marshfield Medical Center
RECRUITING

Marshfield, Wisconsin, 54449, United States
Medical University of South Carolina Hollings Cancer Center
RECRUITING

Charleston, South Carolina, 29425, United States
Minnesota Oncology Hematology
RECRUITING

Burnsville, Minnesota, 55337, United States
Moffitt Cancer Center
RECRUITING

Tampa, Florida, 33612, United States
Nebraska Cancer Specialists
RECRUITING

Grand Island, Nebraska, 68803, United States
Northwest Cancer Specialists
RECRUITING

Vancouver, Washington, 98686, United States
Oncology & Hematology Associates of Southwest Virginia
RECRUITING

Blacksburg, Virginia, 24073, United States
Oncology Associates of Oregon
RECRUITING

Eugene, Oregon, 97401, United States
Oncology Hematology Care Clinical Trials
RECRUITING

Cincinnati, Ohio, 45226, United States
Rocky Mountain Cancer Centers
RECRUITING

Lone Tree, Colorado, 80124, United States
SCRI Oncology Partners
RECRUITING

Nashville, Tennessee, 37203, United States
Southern Cancer Center
RECRUITING

Daphne, Alabama, 36526, United States
Texas Oncology-Baylor Charles A. Sammons Cancer Center
RECRUITING

Dallas, Texas, 75246, United States
The Oncology Institute of Hope and Innovation
RECRUITING

Long Beach, California, 90805, United States
The Oncology Institute of Hope and Innovation
RECRUITING

Fort Lauderdale, Florida, 33316, United States
UPMC Hillman Cancer Center
WITHDRAWN

Pittsburgh, Pennsylvania, 15232, United States
University Hospital - Cleveland Medical Center
RECRUITING

Cleveland, Ohio, 44106, United States
University of Maryland Greenebaum Comprehensive Cancer Center
RECRUITING

Baltimore, Maryland, 21201, United States
University of Texas Southwestern Medical Center
RECRUITING

Dallas, Texas, 75390, United States
Universtity of Virginia Health System
COMPLETED

Charlottesville, Virginia, 22908, United States
Virginia Cancer Specialists Research Institute
RECRUITING

Fairfax, Virginia, 22031, United States
Zangmeister Cancer Center
RECRUITING

Columbus, Ohio, 43219, United States

Conditions

Explore the condition pages connected to this study.

SMALL CELL LUNG CANCER