Which GERD syrup works best? new study pits alginate against sucralfate

NCT ID NCT07310927

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether alginate (Gaviscon) or sucralfate (Ulsanic) provides better symptom relief for people with GERD who are already taking acid-reducing medication (PPIs). 140 adults with frequent severe heartburn took one of the two syrups before meals. Researchers measured symptom severity and quality of life using questionnaires. The goal was to see which add-on treatment works best and is easier to tolerate.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Alginate (Gaviscon) and Sucralfate (Ulsanic)

What this could lead to

If this works, it could show that adding alginate or sucralfate to standard PPI therapy provides better symptom relief for people with GERD.

What could go wrong

This is a completed Phase 2/3 trial with 140 participants, but it compares two existing drugs, so it is not a breakthrough. Results may not apply to everyone with GERD, especially those with certain health conditions.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

gastroesophageal reflux disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cmh Lahore

    Lahore, Punjab Province, 54180, Pakistan