Which GERD syrup works best? new study pits alginate against sucralfate

NCT ID NCT07310927

Completed Symptom relief Sponsor: CMH Lahore Medical College and Institute of Dentistry Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 16, 2026 · Updated 3 times

Summary

This study tested whether alginate (Gaviscon) or sucralfate (Ulsanic) provides better symptom relief for people with GERD who are already taking acid-reducing medication (PPIs). 140 adults with frequent severe heartburn took one of the two syrups before meals. Researchers measured symptom severity and quality of life using questionnaires. The goal was to see which add-on treatment works best and is easier to tolerate.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Alginate (Gaviscon) and Sucralfate (Ulsanic)
What this could lead to: If this works, it could show that adding alginate or sucralfate to standard PPI therapy provides better symptom relief for people with GERD.
What could go wrong: This is a completed Phase 2/3 trial with 140 participants, but it compares two existing drugs, so it is not a breakthrough. Results may not apply to everyone with GERD, especially those with certain health conditions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

gastroesophageal reflux disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GERD

Contacts and locations

Locations

Cmh Lahore

Lahore, Punjab Province, 54180, Pakistan

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