New combo tackles tough liver cancer in tiny trial

NCT ID NCT06354387

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This small pilot study tested a combination of two drugs, alectinib and nivolumab, in 5 adults with advanced liver cancer that had not responded to standard treatments. The goal was to see if the combination could shrink tumors. Because it was a very early phase 1 trial with very few participants, the results are preliminary and not enough to draw firm conclusions.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Alectinib (Alecensa) and Nivolumab (Opdivo)
What this could lead to
If it works, this could point toward a new combination treatment for advanced liver cancer patients who have run out of options.
What could go wrong
This is a very early, tiny pilot study with only 5 participants, so results may not apply to others. The combination may cause side effects or fail to shrink tumors.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CMUH

    Taichung, Taiwan

More trials for these conditions

Other studies related to the condition(s) this trial covers.