New combo tackles tough liver cancer in tiny trial
NCT ID NCT06354387
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This small pilot study tested a combination of two drugs, alectinib and nivolumab, in 5 adults with advanced liver cancer that had not responded to standard treatments. The goal was to see if the combination could shrink tumors. Because it was a very early phase 1 trial with very few participants, the results are preliminary and not enough to draw firm conclusions.
What this could mean
Our plain-language read of the trial. This is informational only โ not medical advice or a prediction.
- Active substance
- Alectinib (Alecensa) and Nivolumab (Opdivo)
- What this could lead to
- If it works, this could point toward a new combination treatment for advanced liver cancer patients who have run out of options.
- What could go wrong
- This is a very early, tiny pilot study with only 5 participants, so results may not apply to others. The combination may cause side effects or fail to shrink tumors.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
CMUH
Taichung, Taiwan
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Other studies related to the condition(s) this trial covers.
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