New drug cocktail aims to beat tough lymphoma

NCT ID NCT07001384

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase study tests a combination of two drugs, alectinib and duvelisib, in 30 people with a rare type of blood cancer called ALK-positive anaplastic large cell lymphoma that has come back or not responded to prior treatment. The goal is to find a safe dose and see if the combination can lead to lasting remission after treatment ends.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

alectinib and duvelisib

What this could lead to

If successful, this could provide a new, time-limited treatment option for people with relapsed or refractory ALK+ ALCL, potentially leading to long-term remission without continuous therapy.

What could go wrong

This is a very early Phase 1 trial with only 30 participants, so safety and effectiveness are not yet proven. The combination may cause significant side effects or fail to control the cancer long-term.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

ALK-positive anaplastic large cell lymphoma anaplastic large cell lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-••••

Locations

  • Memorial Sloan Kettering Basking Ridge (LimitedProtocol Activities)

    RECRUITING

    Basking Ridge, New Jersey, 07920, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Bergen (Limited Protocol Activities)

    RECRUITING

    Montvale, New Jersey, 07645, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Cancer Center (All Protocol Activities)

    RECRUITING

    New York, New York, 10065, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Monmouth (Limited Protocol Activities)

    RECRUITING

    Middletown, New Jersey, 07748, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Nassau (Limited Protocol Activities)

    RECRUITING

    Uniondale, New York, 11553, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Suffolk - Commack (Limited Protocol Activities)

    RECRUITING

    Commack, New York, 11725, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Westchester (Limited Protocol Activities)

    RECRUITING

    Harrison, New York, 10604, United States

    Contact Phone: •••-•••-••••