Liver biopsies reveal Fat-Busting secrets in alcohol detox

NCT ID NCT07191561

First seen Jun 24, 2026 · Last updated Jul 24, 2026 · Updated 20 times

Summary

This study looks at how the liver processes fat in people with alcohol use disorder who are quitting drinking. Researchers will take two small liver samples—one early in detox and one after four weeks—to compare gene activity. The goal is to understand how the liver clears fat when alcohol is removed, which could help develop future treatments for alcohol-related liver disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could reveal how the liver recovers from alcohol-related fat buildup, pointing toward new ways to treat or prevent liver damage.
What could go wrong
This is a very small, early-stage observational study with only 25 participants. It does not test a treatment, so results may not lead to direct medical advances.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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