Can alcohol boost the power of nerve blocks for sweaty palms?
NCT ID NCT07788326
First seen Aug 26, 2026 · Last updated Aug 27, 2026 · Updated 1 time
Summary
This trial tests whether adding 20% alcohol to a standard steroid-anesthetic injection into a neck nerve cluster can better treat severe, unexplained palm sweating (palmar hyperhidrosis). Half of the 50 participants will receive the alcohol-enhanced injection, while the other half gets the standard injection alone. The study aims to see if the alcohol version provides more effective or longer-lasting relief from excessive sweating.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- 20% alcohol combined with steroid local anesthetic, injected into the stellate ganglion
- What this could lead to
- If effective, this approach could offer a longer-lasting, minimally invasive treatment option for people with severe palm sweating who haven't found relief from topical treatments.
- What could go wrong
- This is a small, early-stage study, and the addition of alcohol may not improve outcomes or could increase side effects. The procedure carries risks inherent to injections near nerves.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 50 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Oct 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 45 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Age from 18 to 45 years. 2. Both genders. 3. Exhibiting primary palmar hyperhidrosis. 4. All patients with hyperhidrosis and were socially, professionally, and psychologically handicapped. 5. All patients with failed previous dermatological topical treatment as aluminum chloride hexahydrate Exclusion Criteria: 1. An inability of patient to cooperate. 2. Known allergies to alcohol or local anaesthetic.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
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A doctor treating you
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