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Does Weight-Loss surgery change how alcohol hits the body?

NCT ID NCT06257771

Knowledge-focused Sponsor: University of Illinois at Urbana-Champaign Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 08, 2026 · Last updated Sep 09, 2026 · Updated 1 time

Summary

This study looks at how men and women process alcohol after sleeve gastrectomy, a weight-loss surgery. Researchers will give alcohol by mouth or through an IV, both on an empty stomach and after a meal, to see how it affects blood alcohol levels, mood, and blood sugar. They will compare these responses to people who did not have the surgery. The goal is to understand if the surgery changes alcohol's effects and how it impacts blood sugar control.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Alcohol (ethanol) given orally or intravenously
What this could lead to
If it works, this could guide safer alcohol consumption advice and blood sugar management for people after sleeve gastrectomy.
What could go wrong
This is an observational study, not a treatment test. Results may not apply to all patients, and alcohol can cause intoxication and low blood sugar.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 88 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2024

Expected to finish

Aug 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Carle Foundation Hospital and community sample

Ages

21 to 64 years

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Surgery groups: * Male and female, 21-64 yrs. of age * Drink at least 1 standard drink per month but no more than 7 per week (women or \> 14 for men) * Underwent SG surgery 1-5 years ago Non-surgery control group * Male and female who did not undergo bariatric surgery * Age , BMI, race , and alcohol pattern of consumption equivalent to participants in the SG surgery groups Exclusion Criteria: * For all groups (surgery and non-surgery groups) * Smoking or having quit smoking less than 2 months ago * Pregnant or breastfeeding * Taking any medications that might affect alcohol metabolism * Anemia * Gastritis, colitis, Crohn's Disease, malabsorptive diseases, inflammatory diseases, liver disease, kidney disease, cancer less than five years ago, stroke, or severe organ dysfunction * Body weight \>450 pounds (because of a limit on body composition machine) * Alcohol use disorder * Regular use of drugs with addiction potential or regular misuse of substances * Abnormality on EKG as determined by a study physician to present a safety risk

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Conditions

The condition(s) this trial relates to.

hypoglycemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Sleeve gastrectomy

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • University of Illinois at Urbana Champaign

    RECRUITING

    Urbana, Illinois, 61801, United States

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