New radiation technique aims to shield airways and preserve lung function

NCT ID NCT07679607

Not yet recruiting Symptom relief Sponsor: University of Maryland, Baltimore Source: ClinicalTrials.gov ↗

First seen Jul 01, 2026 · Last updated Jul 02, 2026 · Updated 1 time

Summary

This trial compares standard radiation therapy with a new method that specifically avoids damaging small airways in the lungs. The goal is to see if this airway-sparing approach helps patients with stage III non-small cell lung cancer retain better breathing function after treatment. About 70 participants will receive either standard or airway-sparing radiation, and their lung function will be measured at 12 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: airway-sparing radiation therapy (INSPIRE RT)
What this could lead to: If successful, this approach could help lung cancer patients preserve more lung function and improve quality of life after radiation therapy.
What could go wrong: This is a Phase 2 trial with 70 participants, so results are preliminary. The new planning method may not significantly improve breathing or could increase other side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

lung cancer lung neoplasm non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LUNG CANCER (NSCLC) RADIATION

Contacts and locations

Locations

University of Maryland Greenebaum Cancer Center

Baltimore, Maryland, 21201, United States

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