AI could spare many heart patients from risky invasive tests

NCT ID NCT06648239

Completed Diagnosis Sponsor: Hamilton Health Sciences Corporation Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed trial tested whether an artificial intelligence (AI) tool could help doctors decide which low-risk patients with suspected heart disease should get a safer, non-invasive CT scan instead of an invasive angiogram. The study involved 251 adults referred for non-urgent heart testing. The goal was to see if the AI-guided triage could reduce the number of unnecessary invasive procedures, which are costly and carry risks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Artificial intelligence screening tool and cardiac CT angiography
What this could lead to: If successful, this approach could reduce the number of unnecessary invasive heart procedures, making diagnosis safer and cheaper for low-risk patients.
What could go wrong: This was a small, completed trial, so results may not apply to all patients or settings. The AI tool may not always correctly identify who needs invasive testing.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

coronary artery disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CORONARY ARTERY DISEASE

Contacts and locations

Locations

Hamilton General Hospital

Hamilton, Ontario, L8L 2X2, Canada
McMaster University Medical Centre

Hamilton, Ontario, L8N 3Z5, Canada
St. Catharines Hospital

St. Catharines, Ontario, L2S 0A9, Canada

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