AI app aims to catch deadly skin cancer early in rare disease patients

NCT ID NCT05843994

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is developing an artificial intelligence app to detect squamous cell carcinoma (a type of skin cancer) in people with recessive dystrophic epidermolysis bullosa (RDEB), a rare genetic blistering condition. Twenty adults with RDEB and a history of skin cancer will submit photos of their skin through an online survey. The goal is to train the AI to recognize cancer from patient-taken photos, which could eventually lead to a home-use app for early detection.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
online survey and photograph submission
What this could lead to
If successful, this could lead to a home-use app that helps patients and doctors spot skin cancer early, improving outcomes.
What could go wrong
This is an early-stage study with only 20 participants, and the AI may not work as well on real-world photos as it does on professional images.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Department of Dermatology, Northwestern University Feinberg School of Medicine and Lurie Children's Hospital

    Chicago, Illinois, 60611, United States

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