New injection aims to suppress hepatitis b virus

NCT ID NCT07635186

First seen Jun 27, 2026 · Last updated Jul 30, 2026 · Updated 2 times

Summary

This phase 2 trial tests an injection called AHB-137 in adults with chronic hepatitis B who have not yet received treatment. The study compares AHB-137 to a placebo to see if it can lower the amount of hepatitis B virus in the blood and reduce a key marker of infection (HBsAg). Participants will receive multiple doses and be followed for 24 weeks after treatment ends.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
AHB-137
What this could lead to
If successful, AHB-137 could offer a new treatment option that helps control chronic hepatitis B and reduces the risk of liver damage.
What could go wrong
This is an early-phase trial with a small number of participants. The drug may not work as expected or could cause side effects. Results may not apply to all patients.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • AusperBio Investigational Site

    RECRUITING

    Beijing, Beijing Municipality, China

    Contact Email: •••••@•••••

  • AusperBio Investigational Site

    RECRUITING

    Chongqing, Chongqing Municipality, China

    Contact Email: •••••@•••••

  • AusperBio Investigational Site

    RECRUITING

    Xiamen, Fujian, China

    Contact Email: •••••@•••••

  • AusperBio Investigational Site

    RECRUITING

    Guangzhou, Guangdong, China

  • AusperBio Investigational Site

    RECRUITING

    Guangzhou, Guangdong, China

  • AusperBio Investigational Site

    RECRUITING

    Guangzhou, Guangdong, China

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

  • AusperBio Investigational Site

    RECRUITING

    Jiangmen, Guangdong, China

    Contact Email: •••••@•••••

  • AusperBio Investigational Site

    RECRUITING

    Meizhou, Guangdong, China

    Contact Email: •••••@•••••

  • AusperBio Investigational Site

    RECRUITING

    Qingyuan, Guangdong, China

    Contact Email: •••••@•••••

  • AusperBio Investigational Site

    RECRUITING

    Shenzhen, Guangdong, China

  • AusperBio Investigational Site

    RECRUITING

    Shenzhen, Guangdong, China

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

  • AusperBio Investigational Site

    RECRUITING

    Liuzhou, Guangxi, China

    Contact Email: •••••@•••••

  • AusperBio Investigational Site

    RECRUITING

    Wuhan, Hubei, China

  • AusperBio Investigational Site

    RECRUITING

    Wuhan, Hubei, China

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

  • AusperBio Investigational Site

    RECRUITING

    Yichang, Hubei, China

    Contact Email: •••••@•••••

  • AusperBio Investigational Site

    RECRUITING

    Changsha, Hunan, China

  • AusperBio Investigational Site

    RECRUITING

    Changsha, Hunan, China

  • AusperBio Investigational Site

    RECRUITING

    Changsha, Hunan, China

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

  • AusperBio Investigational Site

    RECRUITING

    Nanjing, Jiangsu, China

    Contact Email: •••••@•••••

  • AusperBio Investigational Site

    RECRUITING

    Nanchang, Jiangxi, China

    Contact Email: •••••@•••••

  • AusperBio Investigational Site

    RECRUITING

    Changchun, Jilin, China

    Contact Email: •••••@•••••

  • AusperBio Investigational Site

    RECRUITING

    Shenyang, Liaoning, China

    Contact Email: •••••@•••••

  • AusperBio Investigational Site

    RECRUITING

    Shanghai, Shanghai Municipality, China

  • AusperBio Investigational Site

    RECRUITING

    Shanghai, Shanghai Municipality, China

  • AusperBio Investigational Site

    RECRUITING

    Shanghai, Shanghai Municipality, China

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

  • AusperBio Investigational Site

    RECRUITING

    Xi’an, Shanxi, China

  • AusperBio Investigational Site

    RECRUITING

    Xi’an, Shanxi, China

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

  • AusperBio Investigational Site

    RECRUITING

    Chengdu, Sichuan, China

  • AusperBio Investigational Site

    RECRUITING

    Chengdu, Sichuan, China

  • AusperBio Investigational Site

    RECRUITING

    Chengdu, Sichuan, China

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

  • AusperBio Investigational Site

    RECRUITING

    Kunming, Yunan, China

    Contact Email: •••••@•••••

  • AusperBio Investigational Site

    RECRUITING

    Hangzhou, Zhejiang, China

    Contact Email: •••••@•••••

  • The First Affiliated Hospital of Zhejiang University School of Medicine

    RECRUITING

    Hangzhou, Zhejiang, China

    Contact Email: •••••@•••••

  • The Second Affiliated Hospital of Chongqing Medical University

    RECRUITING

    Chongqing, Chongqing Municipality, China

    Contact Email: •••••@•••••

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